Combination of intra-arterial therapies and sorafenib: is there a clinical benefit?

J Chapiro, R Duran, JF Geschwind - La radiologia medica, 2014 - Springer
Intra-arterial therapies (IATs) play a major role in the treatment of patients with unresectable
hepatocellular carcinoma. Over the last three decades, multiple loco-regional approaches …

Therapeutic options in hepatocellular carcinoma: a comprehensive review

D Suresh, AN Srinivas, A Prashant… - Clinical and …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a chronic liver disease that is highly fatal if not detected
and treated early. The incidence and death rate of HCC have been increasing in recent …

Randomised, multicentre prospective trial of transarterial chemoembolisation (TACE) plus sorafenib as compared with TACE alone in patients with hepatocellular …

M Kudo, K Ueshima, M Ikeda, T Torimura, N Tanabe… - Gut, 2020 - gut.bmj.com
Objective This trial compared the efficacy and safety of transarterial chemoembolisation
(TACE) plus sorafenib with TACE alone using a newly established TACE-specific endpoint …

Sorafenib or placebo plus TACE with doxorubicin-eluting beads for intermediate stage HCC: the SPACE trial

R Lencioni, JM Llovet, G Han, WY Tak, J Yang… - Journal of …, 2016 - Elsevier
Background & Aims Transarterial chemoembolization with doxorubicin-eluting beads (DC
Bead®; DEB-TACE) is effective in patients with Barcelona clinic liver cancer stage B …

NCCN guidelines insights: hepatobiliary cancers, version 1.2017

AB Benson, MI D'Angelica, DE Abbott… - Journal of the National …, 2017 - jnccn.org
The NCCN Guidelines for Hepatobiliary Cancers provide treatment recommendations for
cancers of the liver, gallbladder, and bile ducts. The NCCN Hepatobiliary Cancers Panel …

[HTML][HTML] Sorafenib with or without concurrent transarterial chemoembolization in patients with advanced hepatocellular carcinoma: the phase III STAH trial

JW Park, YJ Kim, SH Bae, SW Paik, YJ Lee, HY Kim… - Journal of …, 2019 - Elsevier
Background & Aims Sorafenib is first-line standard of care for patients with advanced
hepatocellular carcinoma (HCC), yet it confers limited survival benefit. Therefore, we aimed …

Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update

A Gauthier, M Ho - Hepatology Research, 2013 - Wiley Online Library
Sorafenib is the first and only po administrated drug currently approved to treat advanced
hepatocellular carcinoma (HCC). However, concerns have been raised about sorafenib …

[HTML][HTML] 2014 KLCSG-NCC Korea practice guideline for the management of hepatocellular carcinoma

Korean Liver Cancer Study Group - 2015 - gutnliver.org
2014 KLCSG-NCC Korea Practice Guideline for the Management of Hepatocellular
Carcinoma Login to Submission Gut and Liver 2021 Impact Factor 4.321 Indexed In …

The combination of transcatheter arterial chemoembolization and sorafenib is well tolerated and effective in A sian patients with hepatocellular carcinoma: Final …

Y Chao, YH Chung, G Han, JH Yoon… - … journal of cancer, 2015 - Wiley Online Library
This phase II, investigator‐initiated, prospective single‐arm multinational study
(ClinicalTrials. gov registration NCT00990860) evaluated sorafenib in combination with …

Sorafenib alone versus sorafenib combined with transarterial chemoembolization for advanced-stage hepatocellular carcinoma: results of propensity score analyses

GH Choi, JH Shim, MJ Kim, MH Ryu, BY Ryoo… - Radiology, 2013 - pubs.rsna.org
Purpose To compare the time to progression (TTP) and overall survival (OS) in patients with
advanced-stage hepatocellular carcinoma (HCC) who are undergoing sorafenib treatment …