Circulating microRNAs: new biomarkers in diagnosis, prognosis and treatment of cancer

A Allegra, A Alonci, S Campo… - International …, 2012 - spandidos-publications.com
MicroRNAs (miRNAs) are small non-coding, endogenous, single-stranded RNAs. MiRNAs
have been implicated in different areas such as the immune response, neural development …

The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases

JR Finnerty, WX Wang, SS Hébert, BR Wilfred… - Journal of molecular …, 2010 - Elsevier
The miR-15/107 group of microRNA (miRNA) gene is increasingly appreciated to serve key
functions in humans. These miRNAs regulate gene expression involved in cell division …

[HTML][HTML] TGF-β upregulates miR-181a expression to promote breast cancer metastasis

MA Taylor, K Sossey-Alaoui… - The Journal of …, 2013 - Am Soc Clin Investig
Late-stage breast cancer metastasis is driven by dysregulated TGF-β signaling, but the
underlying molecular mechanisms have not been fully elucidated. We attempted to …

MiR-181 family: regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets

R Su, HS Lin, XH Zhang, XL Yin, HM Ning, B Liu… - Oncogene, 2015 - nature.com
MicroRNAs have been shown to play an important role in normal hematopoisis and
leukemogenesis. Here, we report function and mechanisms of miR-181 family in myeloid …

The genetic basis of phenotypic heterogeneity in myelodysplastic syndromes

A Raza, N Galili - Nature Reviews Cancer, 2012 - nature.com
Myelodysplastic syndromes (MDS) are malignant clonal disorders of haematopoietic stem
cells and their microenvironment, affecting older individuals (median age∼ 70 years) …

MicroRNA-155 in serum-derived extracellular vesicles as a potential biomarker for hematologic malignancies-a short report

A Caivano, F La Rocca, V Simeon, M Girasole… - Cellular Oncology, 2017 - Springer
Purpose The use of extracellular vesicles (EVs) from body fluids as “liquid biopsies” is
emerging as a promising approach for the diagnosis, prognosis and therapeutic monitoring …

Circulating microRNAs let-7a and miR-16 predict progression-free survival and overall survival in patients with myelodysplastic syndrome

Z Zuo, GA Calin, HM De Paula… - Blood, The Journal …, 2011 - ashpublications.org
Circulating microRNAs (miRNAs) are potential biomarkers for cancer. We examined plasma
levels of 2 miRNAs, let-7a and miR-16, in 50 patients with myelodysplastic syndrome (MDS) …

Hypoplastic myelodysplastic syndrome and acquired aplastic anemia: Immune-mediated bone marrow failure syndromes

H Votavova, M Belickova - International journal of …, 2021 - spandidos-publications.com
Hypoplastic myelodysplastic syndrome (hMDS) and aplastic anemia (AA) are rare
hematopoietic disorders characterized by pancytopenia with hypoplastic bone marrow (BM) …

Microvesicles from mesenchymal stromal cells are involved in HPC-microenvironment crosstalk in myelodysplastic patients

S Muntion, TL Ramos, M Diez-Campelo, B Roson… - PloS one, 2016 - journals.plos.org
Exosomes/microvesicles (MVs) provide a mechanism of intercellular communication. Our
hypothesis was that mesenchymal stromal cells (MSC) from myelodysplastic syndrome …

Epigenetic silencing of the oncogenic miR‐17‐92 cluster during PU. 1‐directed macrophage differentiation

V Pospisil, K Vargova, J Kokavec, J Rybarova… - The EMBO …, 2011 - embopress.org
The oncogenic cluster miR‐17‐92 encodes seven related microRNAs that regulate cell
proliferation, apoptosis and development. Expression of miR‐17‐92 cluster is decreased …