Isothermal nucleic acid amplification techniques have emerged as an important diagnostic
tool for clinical applications and food safety inspection. Rolling circle amplification (RCA) is …

The introduction of nucleic acid amplification techniques has revolutionized the field of
medical diagnostics in the last decade. The advent of PCR catalyzed the increasing …

Nucleic acids are prominent biomarkers for diagnosing infectious pathogens using nucleic
acid amplification techniques (NAATs). PCR, a gold standard technique for amplifying …

Rolling-circle amplification (RCA) driven by DNA polymerase can replicate circularized
oligonucleotide probes with either linear or geometric kinetics under isothermal conditions …

A novel protein purification system has been developed which enables purification of free
recombinant proteins in a single chromatographic step. The system utilizes a modified …

Rapid, efficient and accurate nucleic acid molecule detection is important in the screening of
diseases and pathogens, yet remains a limiting factor at point of care (POC) treatment …

The DNA polymerase I from Geobacillus stearothermophilus (also known as Bst DNAP) is
widely used in isothermal amplification reactions, where its strand displacement ability is …

Structural genetic alterations in cancer often involve gene loss or gene amplification. With
the advent of microarray approaches for the analysis of the genome, as exemplified by array …

ABSTRACT A new in situ DNA amplification technique for microscopic detection of bacteria
carrying a specific gene is described. Loop-mediated isothermal amplification (LAMP) was …

Disclosed are compositions and a method for amplification of and multiplex detection of
molecules of interest involving rolling circle replication. The method is useful for …