Gastroesophageal reflux disease (GERD) continues to be among the most common
diseases seen by gastroenterologists, surgeons, and primary care physicians. Our …

AIM To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs)
therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a …

Background & Aims Several studies have been published on the association between food
processing and risks of Crohn's disease (CD) and ulcerative colitis (UC), with some …

Proton-pump inhibitors (PPIs) are a widely prescribed class of medications used to treat acid-
related disorders and use has significantly increased over the last few decades. PPIs are …

To identify the relationship between proton-pump inhibitors (PPIs) and the risk of fracture, we
conducted an update meta-analysis of observational studies. Results showed that PPI use …

Background The coexistence of several chronic diseases in one same individual, known as
multimorbidity, is an important challenge facing health care systems in developed countries …

Proton pump inhibitors (PPIs) are known as a class of pharmaceutical agents that target
H+/K+-ATPase, which is located in gastric parietal cells. PPIs are widely used in the …

Background Proton pump inhibitors (PPI) are the most effective drugs for inhibiting gastric
acid secretion. They have been in clinical use for more than 25 years, In 2014, 3.475 billion …

Introduction Emerging epidemiological evidence suggests that proton pump inhibitor (PPI)
acid-suppression therapy is associated with an increased risk of Clostridium difficile …

Background The impact of peri‐operative use of TNF α antagonists on post‐operative
complications such as infection and wound healing is controversial. Aim To conduct a …