Effect of high-fat diets on oxidative stress, cellular inflammatory response and cognitive function

BL Tan, ME Norhaizan - Nutrients, 2019 - mdpi.com
Cognitive dysfunction is linked to chronic low-grade inflammatory stress that contributes to
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …

The prefrontal cortex and obesity: a health neuroscience perspective

CJ Lowe, AC Reichelt, PA Hall - Trends in cognitive sciences, 2019 - cell.com
In the modern obesogenic environment, limiting calorie-dense food consumption is partially
dependent on the capacity of individuals to override visceral reactions to hyperpalatable and …

On the metabolism of exogenous ketones in humans

BJ Stubbs, PJ Cox, RD Evans, P Santer… - Frontiers in …, 2017 - frontiersin.org
Background and aims: Currently there is considerable interest in ketone metabolism owing
to recently reported benefits of ketosis for human health. Traditionally, ketosis has been …

Western diet is associated with a smaller hippocampus: a longitudinal investigation

FN Jacka, N Cherbuin, KJ Anstey, P Sachdev… - BMC medicine, 2015 - Springer
Background Recent meta-analyses confirm a relationship between diet quality and both
depression and cognitive health in adults. While the biological pathways that underpin these …

Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition

MJ Morris, JE Beilharz, J Maniam, AC Reichelt… - Neuroscience & …, 2015 - Elsevier
Abstract Changes in food composition and availability have contributed to the dramatic
increase in obesity over the past 30–40 years in developed and, increasingly, in developing …

A review of the association between obesity and cognitive function across the lifespan: implications for novel approaches to prevention and treatment

E Smith, P Hay, L Campbell, JN Trollor - Obesity reviews, 2011 - Wiley Online Library
Recent research suggests that increased adiposity is associated with poor cognitive
performance, independently of associated medical conditions. The evidence regarding this …

[HTML][HTML] Diet, inflammation and the gut microbiome: mechanisms for obesity-associated cognitive impairment

SJ Leigh, MJ Morris - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …

Energy intake and exercise as determinants of brain health and vulnerability to injury and disease

MP Mattson - Cell metabolism, 2012 - cell.com
Evolution favored individuals with superior cognitive and physical abilities under conditions
of limited food sources, and brain function can therefore be optimized by intermittent dietary …

Interorgan metabolic crosstalk in human insulin resistance

S Gancheva, T Jelenik… - Physiological …, 2018 - journals.physiology.org
Excessive energy intake and reduced energy expenditure drive the development of insulin
resistance and metabolic diseases such as obesity and type 2 diabetes mellitus. Metabolic …

Food reward system: current perspectives and future research needs

M Alonso-Alonso, SC Woods, M Pelchat… - Nutrition …, 2015 - academic.oup.com
This article reviews current research and cross-disciplinary perspectives on the
neuroscience of food reward in animals and humans, examines the scientific hypothesis of …