[HTML][HTML] Challenging cellular homeostasis: Spatial and temporal regulation of miRNAs

N van Wijk, K Zohar, M Linial - International journal of molecular sciences, 2022 - mdpi.com
Mature microRNAs (miRNAs) are single-stranded non-coding RNA (ncRNA) molecules that
act in post-transcriptional regulation in animals and plants. A mature miRNA is the end …

[HTML][HTML] Crosstalk between Long Non-Coding RNA and Spliceosomal microRNA as a Novel Biomarker for Cancer

M Arafat, R Sperling - Non-coding RNA, 2023 - mdpi.com
Non-coding RNAs (ncRNAs) play diverse roles in regulating cellular processes and have
been implicated in pathological conditions, including cancer, where interactions between …

Long noncoding RNA HAGLR sponges miR‐338‐3p to promote 5‐Fu resistance in gastric cancer through targeting the LDHA‐glycolysis pathway

J Hu, L Huang, Q Ding, J Lv… - Cell Biology International, 2022 - Wiley Online Library
Gastric cancer (GC) is one of the most common human malignancies due to its invasiveness
and metastasis. 5‐Fu is a widely applied chemotherapeutic agent against GC. Although 5 …

[HTML][HTML] Identification and roles of miR-29b-1-3p and miR29a-3p-regulated and non-regulated lncRNAs in endocrine-sensitive and resistant breast cancer cells

P Muluhngwi, CM Klinge - Cancers, 2021 - mdpi.com
Simple Summary Estrogen receptor α (ERα) is a key driver and clinical target in breast
cancer, with~ 75% of women having ERα+ breast tumors at diagnosis. Endocrine therapies …

[HTML][HTML] Preoperative serum microRNAs as potential prognostic biomarkers in ovarian clear cell carcinoma

K Suzuki, A Yokoi, K Yoshida, T Kato… - Journal of …, 2023 - ncbi.nlm.nih.gov
Objective Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian carcinoma
with poor prognosis. However, no effective biomarkers have been established for predicting …

[HTML][HTML] APOE Molecular Spectrum in a French Cohort with Primary Dyslipidemia

Y Abou Khalil, O Marmontel, J Ferrières… - International Journal of …, 2022 - mdpi.com
Primary hypercholesterolemia is characterized by elevated LDL-cholesterol (LDL-C) levels
isolated in autosomal dominant hypercholesterolemia (ADH) or associated with elevated …

[HTML][HTML] Selection of endogenous control and identification of significant microRNA deregulations in cervical cancer

T Stverakova, I Baranova, P Mikyskova… - Frontiers in …, 2023 - frontiersin.org
Introduction Cervical cancer causes approximately 350,000 deaths each year. The
availability of sensitive and specific diagnostic tests to detect cervical cancer in its early …

[HTML][HTML] Mudskipper detects combinatorial RNA binding protein interactions in multiplexed CLIP data

H Her, KL Rothamel, GG Nguyen, EA Boyle, GW Yeo - Cell Genomics, 2024 - cell.com
The uncovering of protein-RNA interactions enables a deeper understanding of RNA
processing. Recent multiplexed crosslinking and immunoprecipitation (CLIP) technologies …

[HTML][HTML] HOXD antisense growth-associated long noncoding RNA promotes triple-negative breast cancer progression by activating Wnt signaling pathway

C Zhang, Y Yang, L Yi, X Paizula, W Xu… - Journal of breast …, 2021 - ncbi.nlm.nih.gov
Purpose Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer
owing to high heterogeneity, aggressive nature, and lack of treatment options, which has a …

[HTML][HTML] miRNA Combinatorics and its Role in Cell State Control—A Probabilistic Approach

S Mahlab-Aviv, N Linial, M Linial - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
A hallmark of cancer evolution is that the tumor may change its cell identity and improve its
survival and fitness. Drastic change in microRNA (miRNA) composition and quantities …