Arylacetic acids are widely used in organic reactions and their recent advances are
summarized in six categories according to their triggered pathways:(1) the acid as directing …

Since the first reports of the reaction of imines and cyclic anhydrides by Castagnoli and
Cushman, this procedure has been applied to the synthesis of a variety of lactams, some of …

The mechanisms for the three-and four-component variants of the Castagnoli–Cushman
reaction (CCR) have been investigated. A series of crossover experiments were conducted …

Attempted use of 3-arylglutaconic acids in the three-component version of the Castagnoli–
Cushman reaction with amines and aromatic aldehydes resulted in an unexpected formation …

Novel aryl-substituted homophthalic acids were cyclodehydrated to the respective
homophthalic anhydrides for use in the Castagnoli–Cushman reaction. With a range of …

The earlier reported three-component Castagnoli–Cushman-type synthesis of 1, 4, 6-
trisubstituted 1, 6-dihydropyridin-2-(3 H)-ones from 3-arylglutaconic acids, primary amines …

Abstract The 3, 4‐dihydroisoquinolin‐1 (2H)‐one motifs found in many natural products,
synthetic molecules with a diverse range of the biological activities and represent a privilege …

Realization of the one-pot Staudinger/aza-Wittig/Castagnoli–Cushman reaction sequence
for a series of azido aldehydes and homophthalic anhydrides is described. The reaction …

Cyclic hydroxamic acids can be viewed as effective binders of soluble iron and can therefore
be useful moieties for employing in compounds to treat iron overload disease. Alternatively …

The earlier described reaction of homophthalic anhydrides with aromatic ketones and
ammonium acetate was tested for cyclic ketones (yielding spirocyclic motifs) and aliphatic …