Cellular hypoxia occurs when the demand for sufficient molecular oxygen needed to
produce the levels of ATP required to perform physiological functions exceeds the vascular …

Immunological niches are focal sites of immune activity that can have varying
microenvironmental features. Hypoxia is a feature of physiological and pathological …

Reperfusion injury, the paradoxical tissue response that is manifested by blood flow-
deprived and oxygen-starved organs following the restoration of blood flow and tissue …

Obstructive sleep apnea (OSA) is a complex disorder characterized by collapse of the upper
airway during sleep. Downstream effects involve the cardiovascular, pulmonary, and …

Ischemia and reperfusion–elicited tissue injury contributes to morbidity and mortality in a
wide range of pathologies, including myocardial infarction, ischemic stroke, acute kidney …

Obstructive sleep apnea (OSA) is characterised by recurring episodes of upper airway
obstruction during sleep and the fundamental abnormality reflects the inability of the upper …

The epidemic of obesity has resulted in a parallel incremental burden of nonalcoholic fatty
liver disease (NAFLD) worldwide. Nonalcoholic fatty liver disease includes a spectrum of …

Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

Obstructive sleep apnea (OSA) is an increasingly prevalent sleep disorder characterized by
upper airway obstruction during sleep, resulting in breathing pauses, intermittent hypoxia …

Sleep-induced apnea and disordered breathing refers to intermittent, cyclical cessations or
reductions of airflow, with or without obstructions of the upper airway (OSA). In the presence …