This review presents lower body negative pressure (LBNP) as a unique tool to investigate
the physiology of integrated systemic compensatory responses to altered hemodynamic …

Conventional cardiovascular monitoring may not detect tissue hypoxia, and conventional
cardiovascular support aiming at global hemodynamics may not restore tissue oxygenation …

Shock is deadly and unpredictable if it is not recognized and treated in early stages of
hemorrhage. Unfortunately, measurements of standard vital signs that are displayed on …

Background: Hemorrhagic shock is a leading cause of death in both civilian and battlefield
trauma. Currently available medical monitors provide measures of standard vital signs that …

Trauma patients with “compensated” internal hemorrhage may not be identified with
standard medical monitors until signs of shock appear, at which point it may be difficult or too …

The purpose of this study was to compare hemodynamic and blood analyte responses to
reduced central venous pressure (CVP) and pulse pressure (PP) elicited during graded …

BACKGROUND Hemorrhage is a leading cause of traumatic death. We hypothesized that
state-of-the-art feature extraction and machine learning techniques could be used to …

BACKGROUND: The primary objective of this study was to determine whether alterations in
the pulse oximeter waveform characteristics would track progressive reductions in central …

BACKGROUND Early and accurate detection of severe hemorrhage is critical for a timely
trigger of massive transfusion (MT). Hemodynamic indices combining heart rate (HR) and …

Methods: A prospective observational study of 89 subjects meeting trauma center activation
criteria at a single level I trauma center was conducted from October 2015 to February 2016 …