[HTML][HTML] Understanding the role of neutrophils in acute respiratory distress syndrome

SC Yang, YF Tsai, YL Pan, TL Hwang - Biomedical Journal, 2021 - Elsevier
Acute respiratory distress syndrome (ARDS) is difficult to treat and is associated with a high
mortality rate. The most severe form of coronavirus disease 2019 (COVID-19) also leads to …

Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches

IA Savin, MA Zenkova, AV Sen'kova - International journal of molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …

Neutrophil adaptations upon recruitment to the lung: new concepts and implications for homeostasis and disease

VD Giacalone, C Margaroli, MA Mall… - International journal of …, 2020 - mdpi.com
Neutrophils have a prominent role in all human immune responses against any type of
pathogen or stimulus. The lungs are a major neutrophil reservoir and neutrophilic …

Transfusion-related acute lung injury (TRALI): potential pathways of development, strategies for prevention and treatment, and future research directions

JP Tung, S Chiaretti, MM Dean, AJ Sultana, MC Reade… - Blood Reviews, 2022 - Elsevier
Transfusion-related acute lung injury (TRALI) can occur during or after a transfusion, and
remains a leading cause of transfusion-associated morbidity and mortality. TRALI is caused …

Acute respiratory distress syndrome heterogeneity and the septic ARDS subgroup

H Xu, S Sheng, W Luo, X Xu, Z Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is an acute diffuse inflammatory lung injury
characterized by the damage of alveolar epithelial cells and pulmonary capillary endothelial …

Update on transfusion-related acute lung injury: an overview of its pathogenesis and management

Y Yu, Z Lian - Frontiers in Immunology, 2023 - frontiersin.org
Transfusion-related acute lung injury (TRALI) is a severe adverse event and a leading cause
of transfusion-associated death. Its poor associated prognosis is due, in large part, to the …

Complement activation on endothelium initiates antibody-mediated acute lung injury

SJ Cleary, N Kwaan, JJ Tian… - The Journal of …, 2020 - Am Soc Clin Investig
Antibodies targeting human leukocyte antigen (HLA)/major histocompatibility complex
(MHC) proteins limit successful transplantation and transfusion, and their presence in blood …

Complement activation drives antibody-mediated transfusion-related acute lung injury via macrophage trafficking and formation of NETs

S van der Velden, TLJ van Osch, A Seghier… - Blood, 2024 - ashpublications.org
Transfusion-related acute lung injury (TRALI) is one of the leading causes of transfusion-
related fatalities and, to date, is without available therapies. Here, we investigated the role of …

Association between cardiopulmonary bypass time and mortality among patients with acute respiratory distress syndrome after cardiac surgery

J Hu, Y Liu, L Huang, M Song, G Zhu - BMC Cardiovascular Disorders, 2023 - Springer
Background Cardiopulmonary bypass (CPB) can lead to lung injury and even acute
respiratory distress syndrome (ARDS) through triggering systemic inflammatory response …

Update on the pathophysiology of transfusion-related acute lung injury

EANZ van der Laan, S van der Velden… - Current opinion in …, 2020 - journals.lww.com
Update on the pathophysiology of transfusion-related acute l... : Current Opinion in Hematology
Update on the pathophysiology of transfusion-related acute lung injury : Current Opinion in …