Iridium-catalyzed C–H activation and borylation has become as a powerful synthetic tool in
the past few decades because of the widespread applicability and versatility of organoboron …

Herein, the selective ortho‐and meta‐C− H bond borylation of NH‐aryl sulfoximines is
reported. Regioselectivity is achieved by the choice of commercially available ligands giving …

The indole moiety is ubiquitous in natural products and pharmaceuticals. C–H borylation of
the benzenoid moiety of indoles is a challenging task, especially at the C5 position. We have …

Recent advances in ligand design have enabled Pd (II)-catalyzed nondirected C–H
functionalization using arenes as the limiting reagent, but achieving catalyst control over the …

Site‐selective C− H bond functionalization of arenes at the para position remains extremely
challenging primarily due to its relative inaccessibility from the catalytic site. As a …

Iridium-catalyzed C–H borylation of aromatic and aliphatic hydrocarbons assisted by a
directing group was theoretically investigated. Density functional theory (DFT) calculations …

Achieving positionally selective distal C–H functionalization remains a fundamental and
longstanding challenge in the field of C–H activation. The directing template strategy has …

The boron atom is a highly electrophilic reagent due to the presence of its empty p orbital,
making it prone to undergo electrophilic addition reactions with the carbon–carbon double …

The iridium-catalyzed C–H borylation of benzamides typically leads to meta and para
selectivities using state-of-the-art iridium-based N, N-chelating bipyridine ligands. However …

Regioselective C–H functionalization of aromatics remains a challenging problem in organic
synthesis, particularly for meta-selective C–H borylations of phenols derivatives. Here …