The lymphatic filariasis treatment study landscape: A systematic review of study characteristics and the case for an individual participant data platform

LT Freitas, MA Khan, A Uddin, JB Halder… - PLOS Neglected …, 2024 - journals.plos.org
Background Lymphatic filariasis (LF) is a neglected tropical disease (NTD) targeted by the
World Health Organization for elimination as a public health problem (EPHP). Since 2000 …

Safety and efficacy of mass drug administration with a single-dose triple-drug regimen of albendazole+ diethylcarbamazine+ ivermectin for lymphatic filariasis in …

L Tavul, M Laman, C Howard, B Kotty… - PLoS neglected …, 2022 - journals.plos.org
Background Papua New Guinea (PNG) has a high burden of lymphatic filariasis (LF) caused
by Wuchereria bancrofti, with an estimated 4.2 million people at risk of infection. A single co …

Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor–mediated lymphangiogenesis

J Furlong-Silva, SD Cross, AE Marriott… - The Journal of …, 2021 - Am Soc Clin Investig
Lymphatic filariasis is the major global cause of nonhereditary lymphedema. We
demonstrate that the filarial nematode Brugia malayi induced lymphatic remodeling and …

Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment

S Quek, DAN Cook, Y Wu, AE Marriott… - Proceedings of the …, 2022 - National Acad Sciences
Lymphatic filariasis is a vector-borne neglected tropical disease prioritized for global
elimination. The filarial nematodes that cause the disease host a symbiotic bacterium …

[HTML][HTML] Evaluation of commercial rapid lateral flow tests, alone or in combination, for SARS-CoV-2 antibody testing

PU Fischer, K Fischer, KC Curtis, Y Huang… - The American Journal …, 2021 - ncbi.nlm.nih.gov
Antibody tests can be tools for detecting current or past severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2 [coronavirus disease 2019 (COVID-19)]) infections …

[HTML][HTML] Berberina, curcumina y quercetina como potenciales agentes con capacidad antiparasitaria

JH Elizondo-Luévano, ME Hernández-García… - Revista de Biología …, 2020 - scielo.sa.cr
Introducción: El uso indiscriminado de agentes antiparasitarios ha resultado en el
establecimiento de resistencia a ellos. Por lo cual es necesario el desarrollo de nuevas …

Characterization of a novel microfilarial antigen for diagnosis of Wuchereria bancrofti infections

SE Greene, K Fischer, YJ Choi, KC Curtis… - PLoS neglected …, 2022 - journals.plos.org
Background Lymphatic filariasis (LF) is a neglected tropical disease caused by the filarial
nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. The Global Program to …

Distinguishing recrudescence from reinfection in lymphatic filariasis

YJ Choi, K Fischer, A Méité, BG Koudou, PU Fischer… - …, 2024 - thelancet.com
Summary Background The Global Program to Eliminate Lymphatic Filariasis (GPELF) is the
largest public health program based on mass drug administration (MDA). Despite decades …

[HTML][HTML] Characterization of glycan determinants that mediate recognition of the major Wuchereria bancrofti circulating antigen by diagnostic antibodies

MI Hertz, A Rush, TB Nutman, GJ Weil… - Molecular and …, 2020 - Elsevier
Abstract The Global Program to Eliminate Lymphatic Filariasis (GPELF) relies heavily on a
rapid diagnostic test (RDT) to a Wuchereria bancrofti circulating filarial antigen (Wb-CFA) to …

[HTML][HTML] Filariasis

TE Newman, AL Juergens - 2020 - europepmc.org
Objectives: Identify the etiology of lymphatic filariasis medical conditions and emergencies.
Outline the appropriate history, physical, and evaluation of lymphatic filariasis. Review the …