SARS-CoV-2 infection is characterized by a protean clinical picture that can range from
asymptomatic patients to life-threatening conditions. Severe COVID-19 patients often display …

Since early 2020, the SARS-CoV-2 pandemic has a massive impact on health care systems
worldwide. Patients with malignant diseases are assumed to be at increased risk for a worse …

Objective Haemophagocytic lymphohistiocytosis (HLH) and macrophage activation
syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes that can …

The COVID‐19 pandemic has led to the biggest global health crisis of our lifetime. There is
accumulating evidence that a substantial number of critically ill COVID‐19 patients exhibit a …

Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome driven
by pathologic activation of cytotoxic T-lymphocytes and macrophages. Despite advances in …

Purpose The coronavirus disease 2019 (COVID-19) pandemic has led to the approval of
novel vaccines with different mechanisms of action. Until now, more than 4.7 billion persons …

Haemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome
characterised by persistently activated cytotoxic lymphocytes and macrophages, which, if …

Hemophagocytic lymphocytosis (HLH) is a life-threatening, underdiagnosed syndrome
caused by the excessive release of inflammatory mediators. Primary lymphocytosis is …

Simple Summary CD19+ Chimeric antigen receptor (CAR) T-cells are used against CD19+
hematologic malignancies, such as high-grade B-cell lymphoma and acute lymphoblastic …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits an interferon (IFN)
deficiency state, which aggravates the type I interferon deficiency and slow IFN responses …