COX-2 and its inhibition as a molecular target in the prevention and treatment of lung cancer

Z Liao, L Milas - Expert review of anticancer therapy, 2004 - Taylor & Francis
Lung cancer is the leading cause of cancer death in the USA. Conventional therapy using
chemotherapy, radiation therapy, and a combination of the two, has yielded modest …

Expression of cyclo-oxygenase-2 in macrophages associated with cutaneous melanoma at different stages of progression

F Bianchini, D Massi, C Marconi, A Franchi… - Prostaglandins & other …, 2007 - Elsevier
The biological significance of the almost constant presence of macrophages in the tumoral
microenvironment is an issue debated by several authors. The major difficulty in …

COX-2 and NF-KB overexpression is common in pancreatic cancer but does not predict for COX-2 inhibitors activity in combination with gemcitabine and oxaliplatin

S Cascinu, M Scartozzi, G Carbonari… - American journal of …, 2007 - journals.lww.com
Objective: The attempt to improve therapeutic results in pancreatic carcinoma has recently
focused on the emerging role of molecular biology. We investigated the role of COX-2 and …

[HTML][HTML] RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer

RD Church, J Yu, JW Fleshman, WD Shannon… - British journal of …, 2004 - nature.com
Abstract Cyclooxygenases (particularily Cox-2) are involved in carcinogenesis and
metastatic cancer progression. The expression profiles of the cyclooxygenases and the roles …

PENGARUH MELOXICAM TERHADAP JUMLAH SEL DARAH TEPI TIKUS WISTAR YANG DIBERIKAN CYCLOPHOSPHAMIDE

DP Indriatmoko - 2012 - eprints.undip.ac.id
Latar belakang: Cyclophosphamide dapat mensupresi jumlah sel darah tepi akibat
kematian sel-sel hematopoietik disertai hambatan terhadap stimulator hematopoietik …

[PDF][PDF] Genoprotektive Effekte von Celebrex und Mutagensensitivität im CyclinD1 bei Patienten mit und ohne Plattenepithelkarzinom des oberen Aerodigestivtraktes

M Hartmann - 2009 - edoc.ub.uni-muenchen.de
Mutationen in Regulations-, Wachstums-oder Differenzierungsgenen können dabei zur
tumorösen Entartung von Körperzellen führen, die dadurch in der Lage sind ein autonomes …

Design and synthesis of novel amide and dithiocarbamate ester analogs of podocarpic acid and the 7-alkyl substituted testosterone derivatives for studies in prostate …

C Mouamba - 2010 - search.proquest.com
The work described in this dissertation involves the synthesis and characterization of
derivatives of two natural products, podocarpic acid and testosterone. In addition, the …

[PDF][PDF] IL MICROAMBIENTE TUMORALE NEI MECCANISMI DI PROGRESSIONE NEOPLASTICA IL MICROAMBIENTE TUMORALE NEI MECCANISMI DI …

C Marconi - 2008 - flore.unifi.it
RIASSUNTO L'effetto più devastante della crescita tumorale è rappresentato dalla diffusione
metastatica negli organi secondari. La cellula neoplastica che si distacca dal tumore di …

[图书][B] UVB-induced inflammation and carcinogenesis in immunosuppressed mice

JL Hatton - 2005 - search.proquest.com
Ultraviolet light B (UVB) is a ubiquitous complete carcinogen of the skin. Due to their
immunosuppressive therapy, organ transplant recipients have a 60–250 fold increased …