Cell transplantation, as a therapeutic intervention for spinal cord injury (SCI), has been
extensively studied by researchers in recent years. A number of different kinds of stem cells …

Olfactory ensheathing cells (OECs) constitute a unique population of glia that accompany
and ensheath the primary olfactory axons. They are thought to be critical for spontaneous …

Electrical stimulation (ES) applied to a conductive nerve graft holds the great potential to
improve nerve regeneration and functional recovery in the treatment of lengthy nerve …

Metformin, the popular anti-diabetic drug was shown to exert multiple biological effects. The
most recent metformin gained attention as an agent that mobilizes endogenous progenitor …

Damage to the brain and spinal cord leads to permanent functional disability because of the
very limited capacity of the central nervous system (CNS) for repair. Transplantation of cells …

Dogs can be used as a translational animal model to close the gap between basic
discoveries in rodents and clinical trials in humans. The present study compared the species …

The low-affinity nerve growth factor receptor p75NTR is a major neurotrophin receptor
involved in manifold and pleiotropic functions in the developing and adult central nervous …

Olfactory ensheathing cells (OECs) have become a popular candidate for the transplant-
mediated repair of the damaged CNS. In this review a description is made of the origins of …

Better understanding of the pathogenesis of spinal cord injury (SCI) is needed for the
development of new therapeutic strategies. Spinal cord injury has been investigated in …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …