Treatment of Pseudomonas aeruginosa infectious biofilms: Challenges and strategies

R Yin, J Cheng, J Wang, P Li, J Lin - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa, a Gram-negative bacterium, is one of the major pathogens
implicated in human opportunistic infection and a common cause of clinically persistent …

[HTML][HTML] Preclinical data and safety assessment of phage therapy in humans

JY Nale, MRJ Clokie - Current opinion in biotechnology, 2021 - Elsevier
Highlights•Phages kill antibiotic resistant/sensitive bacteria so are promising
therapeutics.•Safety and efficacy phage data is needed to motivate clinical trials.•Careful in …

Bacteriophages and lysins in biofilm control

M Łusiak-Szelachowska, B Weber-Dąbrowska… - Virologica Sinica, 2020 - Springer
To formulate the optimal strategy of combatting bacterial biofilms, in this review we update
current knowledge on the growing problem of biofilm formation and its resistance to …

Safety Properties of Escherichia coli O157:H7 Specific Bacteriophages: Recent Advances for Food Safety

BO Oluwarinde, DJ Ajose, TO Abolarinwa, PK Montso… - Foods, 2023 - mdpi.com
Shiga-toxin-producing Escherichia coli (STEC) is typically detected on food products mainly
due to cross-contamination with faecal matter. The serotype O157: H7 has been of major …

Bacteriophages and antibiotic interactions in clinical practice: what we have learned so far

M Łusiak-Szelachowska, R Międzybrodzki… - Journal of Biomedical …, 2022 - Springer
Bacteriophages (phages) may be used as an alternative to antibiotic therapy for combating
infections caused by multidrug-resistant bacteria. In the last decades, there have been …

Therapeutic Effect of a Newly Isolated Lytic Bacteriophage against Multi-Drug-Resistant Cutibacterium acnes Infection in Mice

HYP Lam, MJ Lai, TY Chen, WJ Wu, SY Peng… - International Journal of …, 2021 - mdpi.com
Acne vulgaris, which is mostly associated with the colonization of Cutibacterium acnes (C.
acnes), is a common skin inflammatory disease in teenagers. However, over the past few …

Engineering pH-sensitive erodible chitosan hydrogel composite containing bacteriophage: An interplay between hydrogel and bacteriophage against Staphylococcus …

R Wang, YJ Yeh, YN An - International Journal of Biological …, 2023 - Elsevier
Encapsulation of phages represents a key approach for improving phage stability and
controlling phage delivery dosage. The hydrogel made from positively charged quaternized …

Phage and phage cocktails formulations

I Mani - Progress in Molecular Biology and Translational …, 2023 - Elsevier
Antibiotic-resistant bacterial infection is a major global problem and can be life-threatening.
Bacteriophages or phages can be substituted choice over traditional antibiotics treatments …

Phage therapy in tackling AMR: potential and prospects

T Anand, M Vashisth, A Jaglan… - Indian Journal of …, 2022 - indianjournals.com
Bacteriophages, usually known as phages, are the natural predators of bacteria. They reside
in the habitats where bacteria are found and are abundant in nature including soil, water …

Monitoring Bacteriophage Infection on Bacterial Cells Using FISH

D Vilas-Boas, LDR Melo - Fluorescence In-Situ Hybridization (FISH) for …, 2021 - Springer
The possibility of visualizing bacteriophage-host interactions through fluorescence in situ
hybridization (FISH)-derived methods is gaining relevance in the last few years. These …