Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post‐genome era

T Raudsepp, CJ Finno, RR Bellone… - Animal …, 2019 - Wiley Online Library
The horse reference genome from the Thoroughbred mare Twilight has been available for a
decade and, together with advances in genomics technologies, has led to unparalleled …

[HTML][HTML] Improved reference genome for the domestic horse increases assembly contiguity and composition

TS Kalbfleisch, ES Rice, MS DePriest Jr… - Communications …, 2018 - nature.com
Recent advances in genomic sequencing technology and computational assembly methods
have allowed scientists to improve reference genome assemblies in terms of contiguity and …

[HTML][HTML] Genetic variation and the distribution of variant types in the horse

SA Durward-Akhurst, RJ Schaefer, B Grantham… - Frontiers in …, 2021 - frontiersin.org
Genetic variation is a key contributor to health and disease. Understanding the link between
an individual's genotype and the corresponding phenotype is a major goal of medical …

[HTML][HTML] Genome-wide homozygosity patterns and evidence for selection in a set of European and near eastern horse breeds

G Grilz-Seger, M Neuditschko, A Ricard, B Velie… - Genes, 2019 - mdpi.com
Intensive artificial and natural selection have shaped substantial variation among European
horse breeds. Whereas most equine selection signature studies employ divergent genetic …

Genetic testing in the horse

RR Bellone, F Avila - Veterinary Clinics: Equine Practice, 2020 - vetequine.theclinics.com
Genetic testing in horses began with parentage using blood testing (blood group and protein
polymorphism tests) in the 1960s. Methods to identify and evaluate genetic variants at the …

Risk factors for equine recurrent uveitis in a population of Appaloosa horses in western Canada

LS Sandmeyer, NB Kingsley, C Walder… - Veterinary …, 2020 - Wiley Online Library
Objective To characterize clinical manifestations, measure frequency, and evaluate risk
factors for equine recurrent uveitis (ERU) in Appaloosa horses in western Canada. Animals …

Diseases of the equine cornea

DE Brooks, CE Plummer - Equine ophthalmology, 2022 - Wiley Online Library
The precorneal tear film is classically described as a trilaminar structure adherent to and
covering the external cornea, forming an integral and important physicochemical component …

[HTML][HTML] Intralesional interferon alpha-2b as a novel treatment for periocular squamous cell carcinoma in horses

BB Martabano, S Dow, L Chow, MMV Williams… - Plos one, 2024 - journals.plos.org
Objective To determine the safety and efficacy of perilesional human recombinant interferon
alpha-2b (IFNα2b) for treatment of periocular squamous cell carcinoma (PSCC) in horses …

Genome‐wide survey on three local horse populations with a focus on runs of homozygosity pattern

A Criscione, S Mastrangelo… - Journal of Animal …, 2022 - Wiley Online Library
Abstract Purosangue Orientale Siciliano, Sanfratellano and Siciliano represent the Sicilian
equine genetic resource. This study aimed to investigate the genetic diversity, population …

Genetic risk for squamous cell carcinoma of the nictitating membrane parallels that of the limbus in Haflinger horses

M Singer‐Berk, KE Knickelbein, S Vig, J Liu… - Animal …, 2018 - Wiley Online Library
Squamous cell carcinoma (SCC) is the most common cancer affecting the equine eye, with a
higher incidence documented in Haflinger horses. Recently, a missense variant in the gene …