Association between insulin resistance and the development of cardiovascular disease
V Ormazabal, S Nair, O Elfeky, C Aguayo… - Cardiovascular …, 2018 - Springer
For many years, cardiovascular disease (CVD) has been the leading cause of death around
the world. Often associated with CVD are comorbidities such as obesity, abnormal lipid …
the world. Often associated with CVD are comorbidities such as obesity, abnormal lipid …
Obesity, kidney dysfunction and hypertension: mechanistic links
JE Hall, JM do Carmo, AA da Silva, Z Wang… - Nature reviews …, 2019 - nature.com
Excessive adiposity raises blood pressure and accounts for 65–75% of primary
hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity …
hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity …
Overview of epidemiology and contribution of obesity and body fat distribution to cardiovascular disease: an update
Obesity is recognized as a heterogeneous condition in which individuals with similar body
mass index may have distinct metabolic and cardiovascular risk profiles. Susceptibility to …
mass index may have distinct metabolic and cardiovascular risk profiles. Susceptibility to …
Impaired adipogenesis and dysfunctional adipose tissue in human hypertrophic obesity
A Hammarstedt, S Gogg, S Hedjazifar… - Physiological …, 2018 - journals.physiology.org
The subcutaneous adipose tissue (SAT) is the largest and best storage site for excess lipids.
However, it has a limited ability to expand by recruiting and/or differentiating available …
However, it has a limited ability to expand by recruiting and/or differentiating available …
Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance
Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes,
and can accelerate diabetes-related microvascular and macrovascular complications by …
and can accelerate diabetes-related microvascular and macrovascular complications by …
[HTML][HTML] Pathophysiology of obesity and its associated diseases
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …
studies have indicated that obesity strongly contributes to the development of cancer …
[HTML][HTML] α-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury
M Wallert, M Ziegler, X Wang, A Maluenda, X Xu… - Redox biology, 2019 - Elsevier
Objective Myocardial infarction (MI) is a leading cause of mortality and morbidity worldwide
and new treatment strategies are highly sought-after. Paradoxically, reperfusion of the …
and new treatment strategies are highly sought-after. Paradoxically, reperfusion of the …
The role of CD36 in cardiovascular disease
H Shu, Y Peng, W Hang, J Nie, N Zhou… - Cardiovascular …, 2022 - academic.oup.com
CD36, also known as the scavenger receptor B2, is a multifunctional receptor widely
expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty …
expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty …
Metabolic alterations in sepsis
W Wasyluk, A Zwolak - Journal of clinical medicine, 2021 - mdpi.com
Sepsis is defined as “life-threatening organ dysfunction caused by a dysregulated host
response to infection”. Contrary to the older definitions, the current one not only focuses on …
response to infection”. Contrary to the older definitions, the current one not only focuses on …
Inflammaging as a common ground for the development and maintenance of sarcopenia, obesity, cardiomyopathy and dysbiosis
G Livshits, A Kalinkovich - Ageing research reviews, 2019 - Elsevier
Sarcopenia, obesity and their coexistence, obese sarcopenia (OBSP) as well as
atherosclerosis-related cardio-vascular diseases (ACVDs), including chronic heart failure …
atherosclerosis-related cardio-vascular diseases (ACVDs), including chronic heart failure …