Synapse dysfunctions in multiple sclerosis

K Schwarz, F Schmitz - International Journal of Molecular Sciences, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic neuroinflammatory disease of the central nervous system
(CNS) affecting nearly three million humans worldwide. In MS, cells of an auto-reactive …

Association of lesion location and fatigue symptoms after ischemic stroke: a VLSM study

J Wang, M Gu, L Xiao, S Jiang, D Yin, Y He… - Frontiers in Aging …, 2022 - frontiersin.org
Background: Poststroke fatigue (PSF) is a common symptom in stroke survivors, yet its
anatomical mechanism is unclear. Our study was aimed to identify which brain lesions are …

Applying multilayer analysis to morphological, structural, and functional brain networks to identify relevant dysfunction patterns

J Casas-Roma, E Martinez-Heras… - Network …, 2022 - direct.mit.edu
In recent years, research on network analysis applied to MRI data has advanced
significantly. However, the majority of the studies are limited to single networks obtained …

Intracortical surface‐based MR diffusivity to investigate neurologic and psychiatric disorders: a review

F Sampedro, J Kulisevsky - Journal of Neuroimaging, 2022 - Wiley Online Library
Diffusion tensor imaging (DTI) allows the quantification of water diffusivity within the cerebral
cortex. Alterations in cortical mean diffusivity (MD) have been suggested to reflect …

Causal relationship between multiple sclerosis and cortical structure: a Mendelian randomization study

D Sun, R Wang, Q Du, Y Zhang, H Chen, Z Shi… - Journal of Translational …, 2024 - Springer
Background Observational studies have suggested an association between multiple
sclerosis (MS) and cortical structure, but the results have been inconsistent. Objective We …

Detection of grey matter microstructural substrates of neurodegeneration in multiple sclerosis

EA Krijnen, AW Russo, E Salim Karam… - Brain …, 2023 - academic.oup.com
Multiple sclerosis features complex pathological changes in grey matter that begin early and
eventually lead to diffuse atrophy. Novel approaches to image grey-matter microstructural …

Diffusion tensor imaging metrics associated with future disability in multiple sclerosis

E Lopez-Soley, E Martinez-Heras, E Solana… - Scientific reports, 2023 - nature.com
The relationship between brain diffusion microstructural changes and disability in multiple
sclerosis (MS) remains poorly understood. We aimed to explore the predictive value of …

[HTML][HTML] Symmetry differences of structural connectivity in multiple sclerosis and healthy state

F Shahbodaghy, L Shafaghi, M Rostampour… - Brain Research …, 2023 - Elsevier
Focal and diffuse cerebral damages occur in Multiple Sclerosis (MS) that promotes profound
shifts in local and global structural connectivity parameters, mainly derived from diffusion …

Metabolite signature of Alzheimer's disease in adults with Down syndrome

V Montal, I Barroeta, A Bejanin… - Annals of …, 2021 - Wiley Online Library
Objective The purpose of this study was to examine the Alzheimer's disease metabolite
signature through magnetic resonance spectroscopy in adults with Down syndrome and its …

Cortical Macro‐and Microstructural Changes in Parkinson's Disease with Probable Rapid Eye Movement Sleep Behavior Disorder

J Pardo, V Montal, A Campabadal, J Oltra… - Movement …, 2024 - Wiley Online Library
Background Evidence regarding cortical atrophy patterns in Parkinson's disease (PD) with
probable rapid eye movement sleep behavior disorder (RBD)(PD‐pRBD) remains scarce …