Although the majority of low-grade, early-stage endometrial cancer patients have good
survival with surgery alone, patients who recur tend to do poorly. Identification of patients at …

The preimplantation embryo has a remarkable ability to execute its developmental program
using regulatory information inherent within itself. Nonetheless, the uterine environment is …

Perfluorooctane sulfonate (PFOS) has been added to Stockholm Convention for global
phase out, but will continue to contribute to the chemical burden in humans for a long time to …

Infertility and subfertility negatively impact the economics and reproductive performance of
cattle. Of note, significant pregnancy loss occurs in cattle during the first month of pregnancy …

Background Previous work demonstrated that there are numerous miRNAs in human
follicular fluids, some of which are associated with reproductive diseases. In the current …

Ovum pickup and in vitro production (IVP) of bovine embryos are replacing traditional
multiple ovulation embryo transfer (MOET) as the primary means for generating transferable …

The specific role of WNT signaling during preimplantation development remains unclear.
Here, we evaluated consequences of activation and inhibition of β-catenin (CTNNB1) …

The WNT signaling system plays an important but paradoxical role in the regulation of
pluripotency. In the cow, IWR-1, which inhibits canonical WNT activation and has WNT …

The Wnt family features conserved glycoproteins that play roles in tissue regeneration,
animal development and cell proliferation and differentiation. For its functional diversity and …

A functional canonical WNT signaling pathway exists in preimplantation embryos and
inhibits embryonic development. Recent studies suggest that this pathway is over-expressed …