Pertussis resurgence: waning immunity and pathogen adaptation–two sides of the same coin

FR Mooi, NAT Van Der Maas… - Epidemiology & Infection, 2014 - cambridge.org
Pertussis or whooping cough has persisted and resurged in the face of vaccination and has
become one of the most prevalent vaccine-preventable diseases in Western countries. The …

Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology tools

NH Carbonetti - Future microbiology, 2010 - Future Medicine
Pertussis toxin and adenylate cyclase toxin are two important virulence factors of Bordetella
pertussis, the bacterial cause of the respiratory disease pertussis or whooping cough. In …

Pertussis disease burden in the household: how to protect young infants

SC de Greeff, FR Mooi, A Westerhof… - Clinical infectious …, 2010 - academic.oup.com
Background. We conducted a population-based, nation-wide, prospective study to identify
who introduced pertussis into the household of infants aged⩽ 6 months admitted to the …

Bordetella pertussis and vaccination: the persistence of a genetically monomorphic pathogen

FR Mooi - Infection, Genetics and Evolution, 2010 - Elsevier
Before childhood vaccination was introduced in the 1950s, pertussis or whooping cough
was a major cause of infant death worldwide. Widespread vaccination of children was …

[HTML][HTML] Seroprevalence of Pertussis in the Netherlands: Evidence for Increased Circulation of Bordetella pertussis

SC de Greeff, HE de Melker, PGM van Gageldonk… - PloS one, 2010 - journals.plos.org
Background In many countries, the reported pertussis has increased despite high
vaccination coverage. However, accurate determination of the burden of disease is …

Perplexities of pertussis: recent global epidemiological trends and their potential causes

DW Jackson, P Rohani - Epidemiology & Infection, 2014 - cambridge.org
Recent much-publicized increases in pertussis case reports in some countries with high
vaccine coverage have raised concerns about its current and future control. The ubiquity of …

Parental refusal of pertussis vaccination is associated with an increased risk of pertussis infection in children

JM Glanz, DL McClure, DJ Magid, MF Daley… - …, 2009 - publications.aap.org
OBJECTIVE. The objective of this study was to determine if children who contracted
pertussis infection were more likely to have parents who refused pertussis vaccinations than …

[HTML][HTML] A Pertussis Outer Membrane Vesicle-Based Vaccine Induces Lung-Resident Memory CD4 T Cells and Protection Against Bordetella pertussis, Including …

ME Zurita, MM Wilk, F Carriquiriborde… - Frontiers in cellular …, 2019 - frontiersin.org
Pertussis is a respiratory infectious disease that has been resurged during the last decades.
The change from the traditional multi-antigen whole-cell pertussis (wP) vaccines to acellular …

Pertussis: a matter of immune modulation

D De Gouw, DA Diavatopoulos… - FEMS microbiology …, 2011 - academic.oup.com
Pertussis, or whooping cough, is a highly contagious, acute respiratory disease of humans
that is caused by the Gram-negative bacterial pathogen Bordetella pertussis. In the face of …

Investigations into the emergence of pertactin-deficient Bordetella pertussis isolates in six European countries, 1996 to 2012

A Zeddeman, M Van Gent, CJ Heuvelman… - …, 2014 - eurosurveillance.org
Investigations into the emergence of pertactin-deficient Bordetella pertussis isolates in six
European countries, 1996 to 2012 Page 1 1 www.eurosurveillance.org Research articles …