Epidemiology and causes of preterm birth

RL Goldenberg, JF Culhane, JD Iams, R Romero - The lancet, 2008 - thelancet.com
This paper is the first in a three-part series on preterm birth, which is the leading cause of
perinatal morbidity and mortality in developed countries. Infants are born preterm at less …

Spontaneous preterm birth: advances toward the discovery of genetic predisposition

JF Strauss III, R Romero, N Gomez-Lopez… - American journal of …, 2018 - Elsevier
Evidence from family and twin-based studies provide strong support for a significant
contribution of maternal and fetal genetics to the timing of parturition and spontaneous …

Spontaneous preterm birth, a clinical dilemma: etiologic, pathophysiologic and genetic heterogeneities and racial disparity

R Menon - Acta obstetricia et gynecologica Scandinavica, 2008 - Taylor & Francis
Preterm labor leading to preterm delivery (< 37 weeks' gestation) affects approximately 5–
7% of live births in developed countries, but significantly higher in developing countries …

Rates of and factors associated with recurrence of preterm delivery

MM Adams, LD Elam-Evans, HG Wilson, DA Gilbertz - Jama, 2000 - jamanetwork.com
ContextInformation about risk of recurrent preterm delivery is useful to clinicians,
researchers, and policy makers for counseling, generating etiologic leads, and measuring …

Racial disparity in the frequency of recurrence of preterm birth

ZAF Kistka, L Palomar, KA Lee, SE Boslaugh… - American journal of …, 2007 - Elsevier
OBJECTIVE: We examined the hypothesis that black race independent of other factors
increases the risk for extreme preterm birth and its frequency of recurrence at a similar …

The use of high‐dimensional biology (genomics, transcriptomics, proteomics, and metabolomics) to understand the preterm parturition syndrome

R Romero, J Espinoza, F Gotsch… - … Journal of Obstetrics …, 2006 - Wiley Online Library
High‐dimensional biology (HDB) refers to the simultaneous study of the genetic variants
(DNA variation), transcription (messenger RNA [mRNA]), peptides and proteins, and …

[HTML][HTML] Pregnancy, parturition and preeclampsia in women of African ancestry

A Nakimuli, O Chazara, J Byamugisha, AM Elliott… - American journal of …, 2014 - Elsevier
Maternal and associated neonatal mortality rates in sub-Saharan Africa remain
unacceptably high. In Mulago Hospital (Kampala, Uganda), 2 major causes of maternal …

Estimating recurrence of spontaneous preterm delivery

MS Esplin, E O'Brien, A Fraser, RA Kerber… - Obstetrics & …, 2008 - journals.lww.com
OBJECTIVE: To identify factors associated with spontaneous preterm birth and to estimate
the risk of its recurrence for the second through fourth births among women in Utah who had …

Genetic contributions to preterm birth: implications from epidemiological and genetic association studies

J Plunkett, LJ Muglia - Annals of medicine, 2008 - Taylor & Francis
Infants born before term (< 37 weeks) have an increased risk of neonatal mortality as well as
other health problems. The increasing rate of preterm birth in recent decades, despite …

Molecular regulation of parturition: the role of the decidual clock

ER Norwitz, EA Bonney… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
The timing of birth is a critical determinant of perinatal outcome. Despite intensive research,
the molecular mechanisms responsible for the onset of labor both at term and preterm …