The role of adipokines in health and disease

VJ Clemente-Suárez, L Redondo-Flórez… - Biomedicines, 2023 - mdpi.com
Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a
low-grade state of inflammation and different pathologies. The present review aims to …

Obesity and diabetes: the increased risk of cancer and cancer-related mortality

EJ Gallagher, D LeRoith - Physiological reviews, 2015 - journals.physiology.org
Obesity and type 2 diabetes are becoming increasingly prevalent worldwide, and both are
associated with an increased incidence and mortality from many cancers. The metabolic …

Resistin in metabolism, inflammation, and disease

D Tripathi, S Kant, S Pandey, NZ Ehtesham - The FEBS journal, 2020 - Wiley Online Library
Resistin is a small secretory protein that has a pleiotropic role in rodents and humans. Both
rodent resistin and human resistin have an extremely stable and high‐order multimeric …

[HTML][HTML] Resistin: A reappraisal

E Acquarone, F Monacelli, R Borghi, A Nencioni… - Mechanisms of ageing …, 2019 - Elsevier
From a biological point of view, aging can be considered a progressive inability of an
organism to react to stress, maintain homeostasis, and survive unfavourable changes during …

Adipose tissue, obesity and adipokines: role in cancer promotion

A Booth, A Magnuson, J Fouts… - … molecular biology and …, 2015 - degruyter.com
Adipose tissue is a complex organ with endocrine, metabolic and immune regulatory roles.
Adipose depots have been characterized to release several adipocytokines that work locally …

Obesity and colorectal cancer

M Bardou, AN Barkun, M Martel - Gut, 2013 - gut.bmj.com
Excess body weight, as defined by the body mass index (BMI), has been associated with
several diseases and includes subjects who are overweight (BMI≥ 25–29.9 kg/m2) or …

[HTML][HTML] Obesity and colorectal cancer: role of adipokines in tumor initiation and progression

S Riondino, M Roselli, R Palmirotta… - World journal of …, 2014 - ncbi.nlm.nih.gov
Obesity-associated diseases account for a large portion of public health challenges. Among
obesity-related disorders, a direct and independent relationship has been ascertained for …

Resistin: insulin resistance to malignancy

P Codoñer-Franch, E Alonso-Iglesias - Clinica chimica acta, 2015 - Elsevier
Adipose tissue is recognized as an endocrine organ that secretes bioactive substances
known as adipokines. Excess adipose tissue and adipose tissue dysfunction lead to …

Circulating adipokines and risk of obesity related cancers: A systematic review and meta-analysis

YS Yoon, AR Kwon, YK Lee, SW Oh - Obesity research & clinical practice, 2019 - Elsevier
Background Obesity can influence on carcinogenesis through alterations in adipokines and
subsequent inflammatory changes. This meta-analysis was aimed to comprehensively …

Resistin: An inflammatory cytokine with multi-faceted roles in cancer

SK Sudan, SK Deshmukh, T Poosarla… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Systemic and organ-confined inflammation has been associated with cancer development
and progression. Resistin, initially described as an adipocyte-derived cytokine in mice, is …