Messenger RNA (mRNA) has received great attention in the prevention and treatment of
various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA …

Tumor microenvironment (TME) takes critical roles in tumor resistance to immune checkpoint
inhibitors (ICIs) including anti-programmed death-1 (PD-1) or anti-programmed death-ligand …

The genetic circuits that allow cancer cells to evade immune killing via epithelial
mesenchymal plasticity remain poorly understood. Here, we showed that mesenchymal-like …

Immune checkpoint blockade (ICB) therapy is a powerful option for cancer treatment.
Despite demonstrable progress, most patients fail to respond or achieve durable responses …

Cancer stem cells (CSCs) drive tumor initiation, progression, and therapeutic resistance due
to their self-renewal and differentiation capabilities. Despite encouraging progress in cancer …

T‐cell engagers (TCEs) represent a breakthrough in hematological malignancy treatment
but are vulnerable to antigen escape and lack a vaccination effect. The “immunologically …

Cancer metastasis is a biologically complex process that remains a major challenge in the
oncology clinic, accounting for nearly all of the mortality associated with malignant …

Simple Summary Cancer stem cells (CSCs) in breast cancer have been identified for almost
two decades. Many outstanding discoveries have established the important functions of …

Triple‐negative breast cancer (TNBC) is the most malignant subtype of breast cancer. TP53,
which has a mutation rate of≈ 70%–80% in TNBC patients, plays oncogenic roles when …

In this study, we focus on investigating the therapeutic effects of camptothesome on treating
metastatic triple-negative breast cancer (TNBC). We elucidate that camptothesome elicited …