Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

The laboratory rat has been used as a surrogate to study human biology for more than a
century. Here we present the first genome-scale network reconstruction of Rattus norvegicus …

Pulmonary arterial hypertension (PAH) is a severe cardiovascular disease that is caused by
the progressive occlusion of the distal pulmonary arteries, eventually leading to right heart …

Microcirculatory alterations displayed by patients with heart failure (HF) induce structural
and functional intestinal changes that may affect normal gut microbial community. At the …

A meta-analysis was performed from 66 references retained from a total of 147 ones. The
aim was to study the relationship between the THI and some physiologic, metabolic and …

Recent studies showed that the circulating stress hormones, epinephrine and
corticosterone/cortisol, are involved in mediating ozone-induced pulmonary effects through …

Particulate matter (PM) is emitted during thermal decomposition of waste. During this
process, aromatic compounds chemisorb to the surface of metal-oxide-containing PM …

Ozone exposure induces neuroendocrine stress response, which causes lymphopenia. It
was hypothesized that ozone-induced increases in stress hormones will temporally follow …

Diabetic cardiomyopathy (DCM) is highly prevalent in type 2 diabetes (T2DM) patients. Zinc
is an important essential trace metal, whose deficiency is associated with various chronic …

We have shown that acute ozone inhalation activates sympathetic-adrenal-medullary and
hypothalamus-pituitary-adrenal stress axes, and adrenalectomy (AD) inhibits ozone-induced …