Metallodrugs are unique: Opportunities and challenges of discovery and development
EJ Anthony, EM Bolitho, HE Bridgewater… - Chemical …, 2020 - pubs.rsc.org
Metals play vital roles in nutrients and medicines and provide chemical functionalities that
are not accessible to purely organic compounds. At least 10 metals are essential for human …
are not accessible to purely organic compounds. At least 10 metals are essential for human …
Conjugated photosensitizers for imaging and PDT in cancer research
JCS Simões, S Sarpaki… - Journal of medicinal …, 2020 - ACS Publications
Early cancer detection and perfect understanding of the disease are imperative toward
efficient treatments. It is straightforward that, for choosing a specific cancer treatment …
efficient treatments. It is straightforward that, for choosing a specific cancer treatment …
Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease
TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …
processes at the molecular and cellular levels in humans and other living systems …
Radioactive 198Au-Doped Nanostructures with Different Shapes for In Vivo Analyses of Their Biodistribution, Tumor Uptake, and Intratumoral Distribution
With Au nanocages as an example, we recently demonstrated that radioactive 198Au could
be incorporated into the crystal lattice of Au nanostructures for simple and reliable …
be incorporated into the crystal lattice of Au nanostructures for simple and reliable …
Applications of radiocomplexes with thiosemicarbazones and bis (thiosemicarbazones) in diagnostic and therapeutic nuclear medicine
GL Parrilha, RG dos Santos, H Beraldo - Coordination Chemistry Reviews, 2022 - Elsevier
Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …
Copper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research
CJ Anderson, R Ferdani - Cancer Biotherapy and …, 2009 - liebertpub.com
Summation Copper-64 (T1/2= 12.7 hours; β+, 0.653 MeV [17.8%]; β−, 0.579 MeV [38.4%])
has decay characteristics that allow for positron emission tomography (PET) imaging and …
has decay characteristics that allow for positron emission tomography (PET) imaging and …
Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy
JL Tatum - International journal of radiation biology, 2006 - Taylor & Francis
Purpose: The Cancer Imaging Program of the National Cancer Institute convened a
workshop to assess the current status of hypoxia imaging, to assess what is known about the …
workshop to assess the current status of hypoxia imaging, to assess what is known about the …
Molecular imaging of hypoxia
Hypoxia, a condition of insufficient O 2 to support metabolism, occurs when the vascular
supply is interrupted, as in stroke or myocardial infarction, or when a tumor outgrows its …
supply is interrupted, as in stroke or myocardial infarction, or when a tumor outgrows its …
[HTML][HTML] PET radiopharmaceuticals for imaging of tumor hypoxia: a review of the evidence
Hypoxia is a pathological condition arising in living tissues when oxygen supply does not
adequately cover the cellular metabolic demand. Detection of this phenomenon in tumors is …
adequately cover the cellular metabolic demand. Detection of this phenomenon in tumors is …
Copper complexes as therapeutic agents
C Duncan, AR White - Metallomics, 2012 - academic.oup.com
The importance of transition metals in biological processes has been well established.
Copper (Cu) is a transition metal that can exist in oxidised and reduced states. This allows it …
Copper (Cu) is a transition metal that can exist in oxidised and reduced states. This allows it …