Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide.
However, its toll is higher in more developed countries. Reasons for vast differences in …

Epidemiologic data indicate a significant increase in the incidence of colorectal cancer in
younger populations in the past three decades. Moreover, recent evidence also …

Pancreatic cancer is the fourth leading cause of cancer-related death among men and
women in the United States. A major challenge in treatment remains patients' advanced …

Importance Obesity, defined as a body mass index (BMI) greater than 30, is associated with
a significant increase in the risk of many cancers and in overall mortality. However, various …

Objective: To formulate clinical practice guidelines for the pharmacological management of
obesity. Participants: An Endocrine Society-appointed Task Force of experts, a …

Pancreatic cancer is one of the solid tumors with the worst prognosis. Five-year survival rate
is less than 10%. Surgical resection is the only potentially curative treatment, but the tumor is …

It remains unclear how obesity worsens treatment outcomes in patients with pancreatic
ductal adenocarcinoma (PDAC). In normal pancreas, obesity promotes inflammation and …

The increasing incidence of obesity and its co-morbid conditions poses a great challenge to
global health. In addition to cardiovascular disease and diabetes, epidemiological data …

Conditions and comorbidities of obesity mirror those of ageing and age‐related diseases.
Obesity and ageing share a similar spectrum of phenotypes such as compromised genomic …

Cancer is currently one of the most important public health problems in the world. Pancreatic
cancer is a fatal disease with poor prognosis. As in most other countries, the health burden …