Red light optogenetics in neuroscience

K Lehtinen, MS Nokia, H Takala - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Optogenetics, a field concentrating on controlling cellular functions by means of light-
activated proteins, has shown tremendous potential in neuroscience. It possesses superior …

The superior colliculus: cell types, connectivity, and behavior

X Liu, H Huang, TP Snutch, P Cao, L Wang… - Neuroscience Bulletin, 2022 - Springer
The superior colliculus (SC), one of the most well-characterized midbrain sensorimotor
structures where visual, auditory, and somatosensory information are integrated to initiate …

[HTML][HTML] Brain-wide neural activity underlying memory-guided movement

S Chen, Y Liu, ZA Wang, J Colonell, LD Liu, H Hou… - Cell, 2024 - cell.com
Behavior relies on activity in structured neural circuits that are distributed across the brain,
but most experiments probe neurons in a single area at a time. Using multiple Neuropixels …

Superior colliculus bidirectionally modulates choice activity in frontal cortex

A Thomas, W Yang, C Wang, SL Tipparaju… - Nature …, 2023 - nature.com
Action selection occurs through competition between potential choice options. Neural
correlates of choice competition are observed across frontal cortex and downstream …

Neural mechanisms for the localization of unexpected external motion

S Chinta, SR Pluta - Nature Communications, 2023 - nature.com
To localize objects during active sensing, animals must differentiate stimuli caused by
volitional movement from real-world object motion. To determine a neural basis for this …

Functional organisation of the mouse superior colliculus

T Wheatcroft, AB Saleem, SG Solomon - Frontiers in neural circuits, 2022 - frontiersin.org
The superior colliculus (SC) is a highly conserved area of the mammalian midbrain that is
widely implicated in the organisation and control of behaviour. SC receives input from a …

[HTML][HTML] Optogenetic activation of the inhibitory nigro-collicular circuit evokes contralateral orienting movements in mice

CA Villalobos, MA Basso - Cell reports, 2022 - cell.com
We report that increasing inhibition from the basal ganglia (BG) to the superior colliculus
(SC) through the substantia nigra pars reticulata (nigra) using in vivo optogenetic activation …

Neuronal modulation in the mouse superior colliculus during covert visual selective attention

L Wang, JP Herman, RJ Krauzlis - Scientific Reports, 2022 - nature.com
Covert visual attention is accomplished by a cascade of mechanisms distributed across
multiple brain regions. Visual cortex is associated with enhanced representations of relevant …

Involvement of superior colliculus in complex figure detection of mice

JL Cazemier, R Haak, TKL Tran, ATY Hsu, M Husic… - Elife, 2024 - elifesciences.org
Object detection is an essential function of the visual system. Although the visual cortex
plays an important role in object detection, the superior colliculus can support detection …

Brainstem inhibitory neurons enhance behavioral feature selectivity by sharpening the tuning of excitatory neurons

Y He, X Chou, A Lavoie, J Liu, M Russo, B Liu - Current Biology, 2024 - cell.com
The brainstem is a hub for sensorimotor integration, which mediates crucial innate
behaviors. This brain region is characterized by a rich population of GABAergic inhibitory …