Red light optogenetics in neuroscience
Optogenetics, a field concentrating on controlling cellular functions by means of light-
activated proteins, has shown tremendous potential in neuroscience. It possesses superior …
activated proteins, has shown tremendous potential in neuroscience. It possesses superior …
The superior colliculus: cell types, connectivity, and behavior
The superior colliculus (SC), one of the most well-characterized midbrain sensorimotor
structures where visual, auditory, and somatosensory information are integrated to initiate …
structures where visual, auditory, and somatosensory information are integrated to initiate …
[HTML][HTML] Brain-wide neural activity underlying memory-guided movement
Behavior relies on activity in structured neural circuits that are distributed across the brain,
but most experiments probe neurons in a single area at a time. Using multiple Neuropixels …
but most experiments probe neurons in a single area at a time. Using multiple Neuropixels …
Superior colliculus bidirectionally modulates choice activity in frontal cortex
Action selection occurs through competition between potential choice options. Neural
correlates of choice competition are observed across frontal cortex and downstream …
correlates of choice competition are observed across frontal cortex and downstream …
Neural mechanisms for the localization of unexpected external motion
To localize objects during active sensing, animals must differentiate stimuli caused by
volitional movement from real-world object motion. To determine a neural basis for this …
volitional movement from real-world object motion. To determine a neural basis for this …
Functional organisation of the mouse superior colliculus
The superior colliculus (SC) is a highly conserved area of the mammalian midbrain that is
widely implicated in the organisation and control of behaviour. SC receives input from a …
widely implicated in the organisation and control of behaviour. SC receives input from a …
[HTML][HTML] Optogenetic activation of the inhibitory nigro-collicular circuit evokes contralateral orienting movements in mice
CA Villalobos, MA Basso - Cell reports, 2022 - cell.com
We report that increasing inhibition from the basal ganglia (BG) to the superior colliculus
(SC) through the substantia nigra pars reticulata (nigra) using in vivo optogenetic activation …
(SC) through the substantia nigra pars reticulata (nigra) using in vivo optogenetic activation …
Neuronal modulation in the mouse superior colliculus during covert visual selective attention
Covert visual attention is accomplished by a cascade of mechanisms distributed across
multiple brain regions. Visual cortex is associated with enhanced representations of relevant …
multiple brain regions. Visual cortex is associated with enhanced representations of relevant …
Involvement of superior colliculus in complex figure detection of mice
JL Cazemier, R Haak, TKL Tran, ATY Hsu, M Husic… - Elife, 2024 - elifesciences.org
Object detection is an essential function of the visual system. Although the visual cortex
plays an important role in object detection, the superior colliculus can support detection …
plays an important role in object detection, the superior colliculus can support detection …
Brainstem inhibitory neurons enhance behavioral feature selectivity by sharpening the tuning of excitatory neurons
The brainstem is a hub for sensorimotor integration, which mediates crucial innate
behaviors. This brain region is characterized by a rich population of GABAergic inhibitory …
behaviors. This brain region is characterized by a rich population of GABAergic inhibitory …