Type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, is a chronic disease
characterized by insulin deficiency due to pancreatic β-cell loss and leads to …

Phenylketonuria (PKU) is an autosomal recessive inborn error of phenylalanine metabolism
caused by deficiency in the enzyme phenylalanine hydroxylase that converts phenylalanine …

A substantial research base developed over the past 30 years provides evidence for the
significant role of psychosocial factors in the management of T1D in children and …

The biopsychosocial model proposes that understanding illness requires understanding the
complex interactions between biology (eg, genes, viruses), psychology (eg, mood, behavior) …

According to many therapy manuals and self-help guides on sexuality, stress is the number
one factor inhibiting sexual desire. However, no sufficient empirical evidence can be found …

Adolescence is the transitional phase of development between childhood and emerging
adulthood that incorporates the biological and psychosocial changes of puberty. It imposes …

Objectives To evaluate health-related quality of life (HRQoL) in patients in different stages of
chronic kidney disease (CKD) up to initiation of dialysis treatment and to explore possible …

Alan M Delamatera, Maartje de Witb, Vincent McDarbyc, Jamil Malikd and Carlo L Acerinie
aDepartment of Pediatrics, University of Miami Miller School of Medicine, Miami, FL, USA; …

Background Patient-reported outcome measures (PROMs) could play an important role in
identifying patients' needs and goals in clinical encounters, improving communication and …

Health-related quality of life (HRQOL) has been recognized as an important outcome, some
contend the most important outcome for children's health care interventions. The PedsQL …