Breast cancer histopathology image analysis: A review
This paper presents an overview of methods that have been proposed for the analysis of
breast cancer histopathology images. This research area has become particularly relevant …
breast cancer histopathology images. This research area has become particularly relevant …
siRNAs: applications in functional genomics and potential as therapeutics
Y Dorsett, T Tuschl - Nature reviews Drug discovery, 2004 - nature.com
Molecules that can specifically silence gene expression are powerful research tools. Much
effort has been put into the development of such molecules and has resulted in the creation …
effort has been put into the development of such molecules and has resulted in the creation …
Automatic nuclei segmentation in H&E stained breast cancer histopathology images
M Veta, PJ Van Diest, R Kornegoor, A Huisman… - PloS one, 2013 - journals.plos.org
The introduction of fast digital slide scanners that provide whole slide images has led to a
revival of interest in image analysis applications in pathology. Segmentation of cells and …
revival of interest in image analysis applications in pathology. Segmentation of cells and …
An extracellular matrix microarray for probing cellular differentiation
CJ Flaim, S Chien, SN Bhatia - Nature methods, 2005 - nature.com
We present an extracellular matrix (ECM) microarray platform for the culture of patterned
cells atop combinatorial matrix mixtures. This platform enables the study of differentiation in …
cells atop combinatorial matrix mixtures. This platform enables the study of differentiation in …
High-throughput RNAi screening in cultured cells: a user's guide
CJ Echeverri, N Perrimon - Nature Reviews Genetics, 2006 - nature.com
RNA interference has re-energized the field of functional genomics by enabling genome-
scale loss-of-function screens in cultured cells. Looking back on the lessons that have been …
scale loss-of-function screens in cultured cells. Looking back on the lessons that have been …
Improving the efficiency of RNA interference in mammals
V Mittal - Nature reviews genetics, 2004 - nature.com
RNA interference (RNAi) has been very successfully applied as a gene-silencing technology
in both plants and invertebrates, but many practical obstacles need to be overcome before it …
in both plants and invertebrates, but many practical obstacles need to be overcome before it …
Systematic genome-wide screens of gene function
AE Carpenter, DM Sabatini - Nature Reviews Genetics, 2004 - nature.com
By using genome information to create tools for perturbing gene function, it is now possible
to undertake systematic genome-wide functional screens that examine the contribution of …
to undertake systematic genome-wide functional screens that examine the contribution of …
Computational framework for simulating fluorescence microscope images with cell populations
A Lehmussola, P Ruusuvuori… - IEEE transactions on …, 2007 - ieeexplore.ieee.org
Fluorescence microscopy combined with digital imaging constructs a basic platform for
numerous biomedical studies in the field of cellular imaging. As the studies relying on …
numerous biomedical studies in the field of cellular imaging. As the studies relying on …
DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications
We describe a one-step method for creating thousands of isolated pico-to microliter-sized
droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid …
droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid …
Pathway mapping tools for analysis of high content data
S Ekins, Y Nikolsky, A Bugrim, E Kirillov… - High content screening …, 2006 - Springer
The complexity of human biology requires a systems approach that uses computational
approaches to integrate different data types. Systems biology encompasses the complete …
approaches to integrate different data types. Systems biology encompasses the complete …