Myocardial fibrosis (MF) represents the underlying pathologic condition of many cardiac
disease, leading to cardiac dysfunction and heart failure (HF). Biopsy studies have shown …

Echocardiography represents a first level technique for the evaluation of coronary artery
disease (CAD) which supports clinicians in the diagnostic and prognostic workup of these …

Aims In patients with heart failure (HF), chronically raised left ventricular (LV) filling
pressures lead to progressive left atrial (LA) dysfunction and fibrosis. We aimed to assess …

The speckle-tracking technique has become an easily accessible, quick-to-use, and
straightforward tool for assessing advanced myocardial function. Achievements in the …

Abstract Aims Advanced heart failure (AdHF) is characterized by variable degrees of left
ventricular (LV) dysfunction, myocardial fibrosis, and raised filling pressures which lead to …

In the past, the identification of myocardial fibrosis was only possible through invasive
histologic assessment. Although endomyocardial biopsy remains the gold standard, recent …

Background Left atrial (LA) size is a marker of disease severity and is related to worse
outcomes in secondary mitral regurgitation (MR). The prognostic value of LA function …

Left atrial (LA) phasic function provides significant insights into the pathophysiology of
cardiovascular disease. LA function is described in three phases: reservoir (atrial filling …

Aims Myocardial work (MW) estimation by pressure-strain loops using speckle tracking
echocardiography (STE) has shown to evaluate left ventricular (LV) contraction overcoming …

Thanks to the improvement in mitral regurgitation (MR) diagnostic and therapeutic
management, with the introduction of minimally invasive techniques which have …