Insect cytochrome P450 monooxygenases (P450s) are well known to be involved in
metabolic detoxification of xenobiotics, such as phytochemicals, insecticides and …

Mosquito-borne diseases, the most well known of which is malaria, are among the leading
causes of human deaths worldwide. Vector control is a very important part of the global …

RNAi is a potent technique for the knockdown of target genes. However, its potential off-
target effects limit the widespread applications in both reverse genetic analysis and genetic …

The fall armyworm (FAW), Spodoptera frugiperda, is a destructive pest native to America and
has recently become an invasive insect pest in China. Because of its rapid spread and great …

The increased urbanization of a growing global population makes imperative the
development of sustainable integrated pest management (IPM) strategies for urban pest …

P450s are known to be critical for the detoxification and/or activation of xenobiotics such as
drugs and pesticides and overexpression of P450 genes can significantly affect the …

Background The western flower thrips, Frankliniella occidentalis (Pergande), is a globally
invasive pest and plant virus vector on a wide array of food, fiber, and ornamental crops. The …

Insects have evolved resistance to almost all insecticides developed for their control.
Multiple mechanisms of resistance, including enhanced metabolism and excretion of …

The adaptation of herbivorous insects to their host plants is hypothesized to be intimately
associated with their ubiquitous development of resistance to synthetic pesticides. However …

The common cutworm, Spodoptera litura, has developed with varying degrees of resistance
to most commonly used insecticides. Cytochrome P450 monooxygenases (P450s) with …