The insect fat body is analogous to vertebrate adipose tissue and liver. In this review, the
new and exciting advancements made in fat body biology in the last decade are …

A genetic screen for mutants that alter circadian rhythms in Drosophila identified the first
clock gene—the period (per) gene. The per gene is a central player within a transcriptional …

Many behavioral and physiological processes in adult insects are influenced by both the
endocrine and circadian systems, suggesting that these two key physiological systems …

To adapt to and anticipate rhythmic changes in the environment such as daily light–dark and
temperature cycles, internal timekeeping mechanisms called biological clocks evolved in a …

The short days of late summer and early fall are the environmental cues that most temperate
insects and other animals use to predict winter's arrival. Although it is still unclear precisely …

A major challenge in translating the positive effects of dietary restriction (DR) for the
improvement of human health is the development of therapeutic mimics. One approach to …

Background Drosophila melanogaster often shows correlations between latitude and
phenotypic or genetic variation on different continents, which suggests local adaptation with …

The transcription factor CLOCK (CLK) is essential for the development and maintenance of
circadian rhythms in Drosophila. However, little is known about how CLK levels are …

The rhythmic pattern of biological processes controlled by light over 24 h is termed the
circadian rhythm. Disturbance of circadian rhythm due to exposure to light at night (LAN) …

Background Circadian clocks are synchronized to the solar day via visual and specialized
photoreceptors. In Drosophila, CRYPTOCHROME (CRY) is a major photoreceptor that …