Overview of paratransgenesis as a strategy to control pathogen transmission by insect vectors

NA Ratcliffe, JP Furtado Pacheco, P Dyson… - Parasites & vectors, 2022 - Springer
This article presents an overview of paratransgenesis as a strategy to control pathogen
transmission by insect vectors. It first briefly summarises some of the disease-causing …

Impact of the microbiome on mosquito-borne diseases

H Shi, X Yu, G Cheng - Protein & Cell, 2023 - academic.oup.com
Mosquito-borne diseases present a significant threat to human health, with the possibility of
outbreaks of new mosquito-borne diseases always looming. Unfortunately, current …

The microbiome and mosquito vectorial capacity: rich potential for discovery and translation

C Cansado-Utrilla, SY Zhao, PJ McCall, KL Coon… - Microbiome, 2021 - Springer
Microbiome research has gained considerable interest due to the emerging evidence of its
impact on human and animal health. As in other animals, the gut-associated microbiota of …

Holobiont perspectives on tripartite interactions among microbiota, mosquitoes, and pathogens

R Zheng, Q Wang, R Wu, PN Paradkar… - The ISME …, 2023 - academic.oup.com
Mosquito-borne diseases like dengue and malaria cause a significant global health burden.
Unfortunately, current insecticides and environmental control strategies aimed at the vectors …

Axenic and gnotobiotic insect technologies in research on host–microbiota interactions

J Wu, Q Wang, D Wang, ACN Wong, GH Wang - Trends in microbiology, 2023 - cell.com
Insects are one of the most important animal life forms on earth. Symbiotic microbes are
closely related to the growth and development of the host insects and can affect pathogen …

Innate immunity in Aedes mosquitoes: from pathogen resistance to shaping the microbiota

B Hixson, R Chen, N Buchon - … Transactions of the …, 2024 - royalsocietypublishing.org
Discussions of host–microbe interactions in mosquito vectors are frequently dominated by a
focus on the human pathogens they transmit (eg Plasmodium parasites and arboviruses) …

Wolbachia dominance influences the Culex quinquefasciatus microbiota

GAM Flores, RP Lopez, CS Cerrudo, MA Perotti… - Scientific Reports, 2023 - nature.com
Microorganisms present in mosquitoes and their interactions are key factors affecting insect
development. Among them, Wolbachia is closely associated with the host and affects …

The axenic and gnotobiotic mosquito: emerging models for microbiome host interactions

B Steven, J Hyde, JC LaReau… - Frontiers in Microbiology, 2021 - frontiersin.org
The increasing availability of modern research tools has enabled a revolution in studies of
non-model organisms. Yet, one aspect that remains difficult or impossible to control in many …

Western Kenyan Anopheles gambiae showing intense permethrin resistance harbour distinct microbiota

D Omoke, M Kipsum, S Otieno, E Esalimba, M Sheth… - Malaria Journal, 2021 - Springer
Background Insecticide resistance poses a growing challenge to malaria vector control in
Kenya and around the world. Following evidence of associations between the mosquito …

Interspecies microbiome transplantation recapitulates microbial acquisition in mosquitoes

KL Coon, S Hegde, GL Hughes - Microbiome, 2022 - Springer
Background Mosquitoes harbor microbial communities that play important roles in their
growth, survival, reproduction, and ability to transmit human pathogens. Microbiome …