The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), is an unprecedented global health crisis. However, therapeutic options for …

Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

Coronavirus belongs to the family of Coronaviridae, comprising single-stranded, positive-
sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been known to cause …

The recent emergence of a novel coronavirus (2019‐nCoV), which is causing an outbreak of
unusual viral pneumonia in patients in Wuhan, a central city in China, is another warning of …

The devastating effects of the recent global pandemic (termed COVID-19 for “coronavirus
disease 2019”) caused by the severe acute respiratory syndrome coronavirus-2 (SARS CoV …

Few human pathogens have been the focus of as much concentrated worldwide attention as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its …

Nucleotide analog inhibitors, including broad-spectrum remdesivir and favipiravir, have
shown promise in in vitro assays and some clinical studies for COVID-19 treatment, this …

Abstract The 2019-novel coronavirus (nCoV) is a major source of disaster in the 21 th
century. However, the lack of specific drugs to prevent/treat an attack is a major need at this …

Despite intense research there is currently no effective vaccine available against the new
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in the later 2019 …

Recent history is punctuated by the emergence of highly pathogenic coronaviruses such as
SARS-and MERS-CoV into human circulation. Upon infecting host cells, coronaviruses …