Role of Clostridium perfringens Necrotic Enteritis B-like Toxin in Disease Pathogenesis

KW Lee, HS Lillehoj - Vaccines, 2021 - mdpi.com
Necrotic enteritis (NE) is a devastating enteric disease caused by Clostridium perfringens
type A/G that impacts the global poultry industry by compromising the performance, health …

The effect of necrotic enteritis challenge on production performance, cecal microbiome, and cecal tonsil transcriptome in broilers

G Akerele, WG Al Hakeem, J Lourenco, RK Selvaraj - Pathogens, 2022 - mdpi.com
The objective of this study was to identify the effects of experimental necrotic enteritis (NE)
infection on the production performance, gut microbiome, and cecal tonsil transcriptome in …

Effects of Eimeria maxima infection doses on growth performance and gut health in dual-infection model of necrotic enteritis in broiler chickens

D Goo, J Choi, H Ko, VSR Choppa, G Liu… - Frontiers in …, 2023 - frontiersin.org
The objective of this study was to investigate the effects of the different doses of Eimeria
maxima (EM) oocysts on growth performance and intestinal health in broiler chickens …

Collagen adhesin protein and necrotic enteritis B-like toxin as biomarkers for early diagnosis of necrotic enteritis in commercial broiler chickens

D Goo, I Park, H Nam, Y Lee, J Sawall, AH Smith… - Poultry Science, 2023 - Elsevier
Mouse monoclonal antibodies (mAbs) reactive with Clostridium perfringens collagen
adhesin protein (CNA) and necrotic enteritis B-like toxin (NetB) were developed. The best …

Development of a new immunodiagnostic tool for poultry coccidiosis using an antigen-capture sandwich assay based on monoclonal antibodies detecting an …

Y Lee, HS Lillehoj - Poultry Science, 2023 - Elsevier
This study was conducted to develop an antigen-capture ELISA that detects an
immunodominant antigen of Eimeria, 3-1E which is present in all Eimeria species, using a …

[HTML][HTML] The effect of gut microbiota-derived carnosine on mucosal integrity and immunity in broiler chickens challenged with Eimeria maxima

I Park, H Nam, Y Lee, SS Wickramasuriya, AH Smith… - Poultry Science, 2024 - Elsevier
In the first study, an in vitro culture system was developed to investigate the effects of
carnosine on macrophage proinflammatory cytokine response using an established chicken …

A Rapid and Simple Assay Correlates In Vitro NetB Activity with Clostridium perfringens Pathogenicity in Chickens

M Hustá, R Ducatelle, F Van Immerseel, E Goossens - Microorganisms, 2021 - mdpi.com
Necrotic enteritis is an important enteric disease in poultry, caused by NetB-producing
Clostridium (C.) perfringens strains. As no straight-forward method to assess the NetB …

[HTML][HTML] Research Note: Clostridium perfringens NetB and CnaA neutralizing nanobodies in feed reduce the incidence of poultry necrotic enteritis

SA Loutet, S Cheung, S Zaytsoff, C Hofacre, MK Jones… - Poultry Science, 2024 - Elsevier
Necrotic enteritis is a devastating disease to poultry caused by the bacterium Clostridium
perfringens. As a novel approach to combating poultry necrotic enteritis, we identified and …

Antibiogram pattern and molecular characterization of Clostridium perfringens isolated from different species.

AM Rizk, AM Asal, A El-Tawab, A Awad… - Benha Veterinary …, 2023 - bvmj.journals.ekb.eg
Clostridium perfringens (C. perfringens) is a foodborne pathogen that represent a high risk
to animals and poultry due to its high outbreak incidences worldwide causing diseases such …

[HTML][HTML] Development of Rapid Detection Kit for Necrotic Enteritis Disease in Poultry using Protein A Agglutination

RS Kurnia, CMH Nugroho, OSM Silaen… - World's Veterinary …, 2024 - cyberleninka.ru
Necrotic enteritis causes significant losses in the global poultry industry, necessitating
accurate diagnosis for effective intervention. This study aimed to develop a diagnostic tool …