Enzyme mimics: advances and applications

E Kuah, S Toh, J Yee, Q Ma… - Chemistry–A European …, 2016 - Wiley Online Library
Enzyme mimics or artificial enzymes are a class of catalysts that have been actively pursued
for decades and have heralded much interest as potentially viable alternatives to natural …

Clonal selection and learning in the antibody system

K Rajewsky - Nature, 1996 - nature.com
Each antibody-producing B cell makes antibodies of unique specificity, reflecting a series of
ordered gene rearrangements which must be successfully performed if the cell is to survive …

[图书][B] Hematology E-Book: Basic Principles and Practice

R Hoffman, EJ Benz, LE Silberstein, H Heslop, J Weitz… - 2022 - books.google.com
Extensively revised, comprehensive content from leading global contributors ensures that
Hematology, 8th Edition, remains your# 1 choice for expert guidance in all areas of this …

B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study

BF Haynes, G Kelsoe, SC Harrison, TB Kepler - Nature biotechnology, 2012 - nature.com
Failure of immunization with the HIV-1 envelope to induce broadly neutralizing antibodies
against conserved epitopes is a major barrier to producing a preventive HIV-1 vaccine …

Deletion of a DNA polymerase β gene segment in T cells using cell type-specific gene targeting

H Gu, JD Marth, PC Orban, H Mossmann, K Rajewsky - Science, 1994 - science.org
Deletion of the promoter and the first exon of the DNA polymerase β gene (pol β) in the
mouse germ line results in a lethal phenotype. With the use of the bacteriophage-derived …

[图书][B] Genomes 5

TA Brown - 2023 - taylorfrancis.com
Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook
about genomes and how they are investigated. As with previous Genomes editions …

The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes

X Su, VM Heatwole, SP Wertheimer, F Guinet… - Cell, 1995 - cell.com
The human malaria parasite Plasmodium faiciparum evades host immunity by varying the
antigenic and adhesive character of infected erythrocytes. We describe a large and …

A zonal organization of odorant receptor gene expression in the olfactory epithelium

KJ Ressler, SL Sullivan, LB Buck - Cell, 1993 - Elsevier
The mechanisms by which mammals discriminate a vast array of diverse odors are poorly
understood. To gain insight into the organizational strategies underlying this discriminatory …

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

H Gu, YR Zou, K Rajewsky - Cell, 1993 - cell.com
We have employed a method based on the Cre-/oxP recombination system of
bacteriophage Pl to generate a mouse strain in which the JH segments and the intron …

[图书][B] Murray and Nadel's textbook of respiratory medicine E-book: 2-volume set

RJ Mason, VC Broaddus, TR Martin, TE King… - 2010 - books.google.com
Murray and Nadel's Textbook of Respiratory Medicine has long been the definitive and
comprehensive pulmonary disease reference. Robert J. Mason, MD now presents the fifth …