Towards targeting the breast cancer immune microenvironment

MA Harris, P Savas, B Virassamy… - Nature Reviews …, 2024 - nature.com
The tumour immune microenvironment is shaped by the crosstalk between cancer cells,
immune cells, fibroblasts, endothelial cells and other stromal components. Although the …

Established breast cancer risk factors and risk of intrinsic tumor subtypes

ME Barnard, CE Boeke, RM Tamimi - … et Biophysica Acta (BBA)-Reviews on …, 2015 - Elsevier
Breast cancer is a heterogeneous disease with multiple intrinsic tumor subtypes. These
subtypes vary in tumor gene expression and phenotype, and are most commonly grouped …

Association of reproductive risk factors and breast cancer molecular subtypes: a systematic review and meta-analysis

X Mao, C Omeogu, S Karanth, A Joshi, C Meernik… - BMC cancer, 2023 - Springer
Background Associations between reproductive factors and breast cancer (BC) risk vary by
molecular subtype (ie, luminal A, luminal B, HER2, and triple negative/basal-like [TNBC]). In …

Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer

EB Callihan, D Gao, S Jindal, TR Lyons… - Breast cancer research …, 2013 - Springer
Previous studies report conflicting data on outcomes of pregnancy-associated breast cancer
(PABC). Our aim was to examine the effect of a postpartum diagnosis on maternal prognosis …

Tumor characteristics and prognosis in women with pregnancy‐associated breast cancer

ALV Johansson, TML Andersson… - … journal of cancer, 2018 - Wiley Online Library
There is evidence of poor prognosis in women with pregnancy‐associated breast cancer
(PABC) diagnosed during pregnancy or within 2 years of delivery. Using a large, population …

Cyclooxygenase-2–dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer

TR Lyons, VF Borges, CB Betts, Q Guo… - The Journal of …, 2014 - Am Soc Clin Investig
Breast involution following pregnancy has been implicated in the high rates of metastasis
observed in postpartum breast cancers; however, it is not clear how this remodeling process …

Multidisciplinary management of breast cancer during pregnancy

SS Shachar, K Gallagher, K McGuire, TM Zagar… - The …, 2017 - academic.oup.com
Background Although breast cancer during pregnancy (BCDP) is rare (occurring with only
0.4% of all BC diagnoses in female patients aged 16–49 years), management decisions are …

Postpartum breast involution reveals regression of secretory lobules mediated by tissue-remodeling

S Jindal, D Gao, P Bell, G Albrektsen, SM Edgerton… - Breast cancer …, 2014 - Springer
Introduction A postpartum diagnosis of breast cancer is an independent predictor of
metastases, however the reason is unknown. In rodents, the window of postpartum …

Clinicopathological features and prognosis of pregnancy associated breast cancer–a matched case control study

L Madaras, KA Kovács, AM Szász, I Kenessey… - Pathology & Oncology …, 2014 - Springer
Abstract Pregnancy Associated Breast Cancer (PABC) manifests during pregnancy or within
a year following delivery. We sought to investigate differences in management, outcome …

Breast cancer during pregnancy: a marked propensity to triple-negative phenotype

S Allouch, I Gupta, S Malik, HF Al Farsi, S Vranic… - Frontiers in …, 2020 - frontiersin.org
Breast and cervical cancers comprise 50% of all cancers during pregnancy. In particular,
gestational breast cancer is considered one of the most aggressive types of cancers, which …