A global view of pulmonary hypertension

MM Hoeper, M Humbert, R Souza, M Idrees… - The Lancet …, 2016 - thelancet.com
Pulmonary hypertension is a substantial global health issue. All age groups are affected with
rapidly growing importance in elderly people, particularly in countries with ageing …

Pulmonary arterial hypertension: pathophysiology and treatment

NSH Lan, BD Massam, SS Kulkarni, CC Lang - Diseases, 2018 - mdpi.com
Pulmonary arterial hypertension (PAH), the first category of pulmonary hypertension, is a
chronic and progressive disorder characterised by angioproliferative vasculopathy in the …

Objectives, design and main findings until 2020 from the Rotterdam Study

MA Ikram, G Brusselle, M Ghanbari… - European journal of …, 2020 - Springer
Abstract The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in
the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical …

Evidence of pulmonary hypertension after SARS-CoV-2 infection in subjects without previous significant cardiovascular pathology

C Tudoran, M Tudoran, VE Lazureanu… - Journal of clinical …, 2021 - mdpi.com
Background: Coronavirus (Covid-19) infection represents a serious medical condition, often
associated with cardiovascular complications, pulmonary hypertension (PH), and right …

Endothelial senescence: a new age in pulmonary hypertension

MK Culley, SY Chan - Circulation research, 2022 - Am Heart Assoc
Pulmonary hypertension is an enigmatic, deleterious disease driven by multiple
heterogeneous causes with a burgeoning proportion of older patients with complex, chronic …

Pulmonary hypertension definition, classification, and epidemiology in Asia

JJ Anderson, EM Lau - JACC: Asia, 2022 - jacc.org
Pulmonary hypertension (PH) is caused by a range of conditions and is important to
recognize as it is associated with increased mortality. Pulmonary arterial hypertension refers …

Validity of echocardiographic tricuspid regurgitation gradient to screen for new definition of pulmonary hypertension

H Gall, A Yogeswaran, J Fuge, N Sommer… - …, 2021 - thelancet.com
Background Currently an echocardiographic threshold for the tricuspid regurgitation
gradient (TRG) of> 31 mmHg is recommended for screening for pulmonary hypertension …

Lung cancer–associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell–immune cell cross-talk

SS Pullamsetti, B Kojonazarov, S Storn, H Gall… - Science Translational …, 2017 - science.org
Dyspnea is a frequent, devastating, and poorly understood symptom of advanced lung
cancer. In our cohort, among 519 patients who underwent a computed tomography scan for …

Mildly elevated pulmonary artery systolic pressure on echocardiography: bridging the gap in current guidelines

M Jankowich, BA Maron, G Choudhary - The Lancet Respiratory …, 2021 - thelancet.com
Pulmonary hypertension is associated with increased morbidity and mortality, and growing
evidence suggests that even mild elevations in pulmonary artery pressure estimated with …

Vitamin C deficiency can lead to pulmonary hypertension: a systematic review of case reports

H Hemilä, AME de Man - BMC Pulmonary Medicine, 2024 - Springer
Background In the early literature, unintentional vitamin C deficiency in humans was
associated with heart failure. Experimental vitamin C deficiency in guinea pigs caused …