Computational flow dynamic analysis in left atrial appendage thrombus formation risk: A review

S Valvez, M Oliveira-Santos, AP Piedade… - Applied Sciences, 2023 - mdpi.com
Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by irregular and rapid
electrical activity in the atria, leading to ineffective contraction and poor blood flow. More …

Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke

A Qureshi, GYH Lip, DA Nordsletten… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …

[HTML][HTML] Pulmonary vein flow split effects in patient-specific simulations of left atrial flow

E Durán, M García-Villalba, P Martínez-Legazpi… - Computers in biology …, 2023 - Elsevier
Disruptions to left atrial (LA) blood flow, such as those caused by atrial fibrillation (AF), can
lead to thrombosis in the left atrial appendage (LAA) and an increased risk of systemic …

The role of the pulmonary veins on left atrial flow patterns and thrombus formation

J Mill, J Harrison, M Saiz-Vivo, C Albors, X Morales… - Scientific Reports, 2024 - nature.com
Atrial fibrillation (AF) is the most common human arrhythmia, forming thrombi mostly in the
left atrial appendage (LAA). However, the relation between LAA morphology, blood patterns …

Multiphysics simulations reveal haemodynamic impacts of patient‐derived fibrosis‐related changes in left atrial tissue mechanics

A Gonzalo, CM Augustin, SF Bifulco… - The Journal of …, 2024 - Wiley Online Library
Stroke is a leading cause of death and disability worldwide. Atrial myopathy, including
fibrosis, is associated with an increased risk of ischaemic stroke, but the mechanisms …

Impact of occluder device configurations in in-silico left atrial hemodynamics for the analysis of device-related thrombus

C Albors, J Mill, AL Olivares, X Iriart… - PLOS Computational …, 2024 - journals.plos.org
Left atrial appendage occlusion devices (LAAO) are a feasible alternative for non-valvular
atrial fibrillation (AF) patients at high risk of thromboembolic stroke and contraindication to …

A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data

A Zingaro, Z Ahmad, E Kholmovski, K Sakata… - Scientific reports, 2024 - nature.com
Stroke, a major global health concern often rooted in cardiac dynamics, demands precise
risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2-VASc …

Computational modeling of hemodynamics and risk of thrombosis in the left atrial appendage using patient-specific blood viscosity and boundary conditions at the …

Z Zhang, J Zhu, M Wu, M Neidlin, WT Wu… - … and Modeling in …, 2023 - Springer
Hemodynamics play a vital role for the risk of thrombosis in the left atrial appendage (LAA)
and left atrium (LA) for patients with atrial fibrillation. Accurate prediction of hemodynamics in …

Slow blood-flow in the left atrial appendage is associated with stroke in atrial fibrillation patients

N Paliwal, HC Park, Y Mao, SJ Hong, Y Lee… - Heliyon, 2024 - cell.com
Background Atrial fibrillation (AF) patients are at high risk of stroke with∼ 90% clots
originating from the left atrial appendage (LAA). Clinical understanding of blood-flow based …

[HTML][HTML] Reduced-order models of wall shear stress patterns in the left atrial appendage from a data-augmented atrial database

J Dueñas-Pamplona, S Rodríguez-Aparicio… - Applied Mathematical …, 2024 - Elsevier
Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia,
affecting over 1% of the population. It is usually triggered by irregular electrical impulses that …