New technologies for examining the role of neuronal ensembles in drug addiction and fear
Correlational data suggest that learned associations are encoded within neuronal
ensembles. However, it has been difficult to prove that neuronal ensembles mediate learned …
ensembles. However, it has been difficult to prove that neuronal ensembles mediate learned …
Chemogenetic tools for causal cellular and neuronal biology
D Atasoy, SM Sternson - Physiological reviews, 2018 - journals.physiology.org
Chemogenetic technologies enable selective pharmacological control of specific cell
populations. An increasing number of approaches have been developed that modulate …
populations. An increasing number of approaches have been developed that modulate …
Visualizing the function and fate of neutrophils in sterile injury and repair
Neutrophils have been implicated as harmful cells in a variety of inappropriate inflammatory
conditions where they injure the host, leading to the death of the neutrophils and their …
conditions where they injure the host, leading to the death of the neutrophils and their …
BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets
BigNeuron is an open community bench-testing platform with the goal of setting open
standards for accurate and fast automatic neuron tracing. We gathered a diverse set of …
standards for accurate and fast automatic neuron tracing. We gathered a diverse set of …
Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality
TN Huang, HC Chuang, WH Chou, CY Chen… - Nature …, 2014 - nature.com
The neuron-specific transcription factor T-box brain 1 (TBR1) regulates brain development.
Disruptive mutations in the TBR1 gene have been repeatedly identified in patients with …
Disruptive mutations in the TBR1 gene have been repeatedly identified in patients with …
[HTML][HTML] Two-photon live imaging of single corneal stem cells reveals compartmentalized organization of the limbal niche
The functional heterogeneity of resident stem cells that support adult organs is incompletely
understood. Here, we directly visualize the corneal limbus in the eyes of live mice and …
understood. Here, we directly visualize the corneal limbus in the eyes of live mice and …
Photoactivatable genetically encoded calcium indicators for targeted neuronal imaging
Circuit mapping requires knowledge of both structural and functional connectivity between
cells. Although optical tools have been made to assess either the morphology and …
cells. Although optical tools have been made to assess either the morphology and …
Rapid Hebbian axonal remodeling mediated by visual stimulation
M Munz, D Gobert, A Schohl, J Poquérusse… - Science, 2014 - science.org
We examined how correlated firing controls axon remodeling, using in vivo time-lapse
imaging and electrophysiological analysis of individual retinal ganglion cell (RGC) axons …
imaging and electrophysiological analysis of individual retinal ganglion cell (RGC) axons …
In vivo optogenetic identification and manipulation of GABAergic interneuron subtypes
Highlights•Focal, low-intensity optogenetic stimulation improves interneuron
characterization.•Diode-probes allow flexible multisite perturbation of interneurons.•Methods …
characterization.•Diode-probes allow flexible multisite perturbation of interneurons.•Methods …
Dexamethasone-induced acute excitotoxic cell death in the developing brain
DA Lanshakov, EV Sukhareva, TS Kalinina… - Neurobiology of …, 2016 - Elsevier
There is substantial evidence that the use of glucocorticoids in neonates is associated with
an increased risk of neurodevelopmental disorders. However, it remains unclear how …
an increased risk of neurodevelopmental disorders. However, it remains unclear how …