What we talk about when we talk about fat

ED Rosen, BM Spiegelman - Cell, 2014 - cell.com
There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

The outer subventricular zone and primate-specific cortical complexification

C Dehay, H Kennedy, KS Kosik - Neuron, 2015 - cell.com
Evolutionary expansion and complexification of the primate cerebral cortex are largely
linked to the emergence of the outer subventricular zone (OSVZ), a uniquely structured …

Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites

A Poran, C Nötzel, O Aly, N Mencia-Trinchant… - Nature, 2017 - nature.com
Pathogens have to balance transmission with persistence. For Plasmodium falciparum, the
most widespread and virulent malaria parasite, persistence within its human host requires …

Dissipative structures in biological systems: bistability, oscillations, spatial patterns and waves

A Goldbeter - … Transactions of the Royal Society A …, 2018 - royalsocietypublishing.org
The goal of this review article is to assess how relevant is the concept of dissipative structure
for understanding the dynamical bases of non-equilibrium self-organization in biological …

SHR and SCR coordinate root patterning and growth early in the cell cycle

CM Winter, P Szekely, V Popov, H Belcher, R Carter… - Nature, 2024 - nature.com
Precise control of cell division is essential for proper patterning and growth during the
development of multicellular organisms. Coordination of formative divisions that generate …

Role of the cAMP pathway in glucose and lipid metabolism

K Ravnskjaer, A Madiraju, M Montminy - Metabolic Control, 2016 - Springer
Abstract 3′–5′-Cyclic adenosine monophosphate (cyclic AMP or cAMP) was first
described in 1957 as an intracellular second messenger mediating the effects of glucagon …

Simultaneous metabolite, protein, lipid extraction (SIMPLEX): a combinatorial multimolecular omics approach for systems biology

C Coman, FA Solari, A Hentschel, A Sickmann… - Molecular & cellular …, 2016 - ASBMB
Interconnected molecular networks are at the heart of signaling pathways that mediate
adaptive plasticity of eukaryotic cells. To gain deeper insights into the underlying molecular …

Control of adipocyte differentiation in different fat depots; implications for pathophysiology or therapy

X Ma, P Lee, DJ Chisholm, DE James - Frontiers in endocrinology, 2015 - frontiersin.org
Adipocyte differentiation and its impact on restriction or expansion of particular adipose
tissue depots have physiological and pathophysiological significance in view of the different …

Elucidating the preadipocyte and its role in adipocyte formation: a comprehensive review

CN Sarantopoulos, DA Banyard, ME Ziegler… - Stem Cell Reviews and …, 2018 - Springer
Adipogenesis is a complex process whereby the multipotent adipose-derived stem cell is
converted to a preadipocyte before terminal differentiation into the mature adipocyte …

[HTML][HTML] Identification of an adipose tissue-resident pro-preadipocyte population

M Chen, S Kim, L Li, S Chattopadhyay, TA Rando… - Cell reports, 2023 - cell.com
Elucidating the transitional stages that define the pathway stem cells progress through
during differentiation advances our understanding of biology and fosters the identification of …