Background Ketamine appears to have a therapeutic role in certain mental disorders, most
notably depression. However, the comparative performance of different formulations of …

Ketamine is a phencyclidine derivative, which functions primarily as an antagonist of the N-
methyl-d-aspartate receptor. It has no affinity for gamma-aminobutyric acid receptors in the …

In recent years, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for
Adult Cancer Pain have undergone substantial revisions focusing on the appropriate and …

Ketamine was introduced into clinical practice in the 1960s and continues to be both
clinically useful and scientifically fascinating. With considerably diverse molecular targets …

After nearly half a century on the market, ketamine still occupies a unique corner in the
medical armamentarium of anesthesiologists or clinicians treating pain. Over the last two …

Ketamine's clinical use began in the 1970s. Physicians benefited from its safety and ability to
induce short-term anesthesia and analgesia. The psychodysleptic effects caused by the …

Moderate to severe pain occurs in many cancer patients during their clinical course and may
stem from the primary pathology, metastasis, or as treatment side effects. Uncontrolled pain …

Ketamine is commonly used as an analgesic in emergency medicine and as an adjuvant
drug in the perioperative setting. In addition, it is used as a third-line adjuvant drug for opioid …

Ketamine as an adjuvant to opioids for cancer pain - Bell, RF - 2017 | Cochrane Library Skip to
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Introduction: Central sensitization (CS) is present in a variety of chronic pain disorders,
including whiplash, temporomandibular disorders, low back pain, osteoarthritis …