Gene electrotransfer is a powerful method of DNA delivery offering several medical
applications, among the most promising of which are DNA vaccination and gene therapy for …

Electroporation is a platform technology for drug and gene delivery. When applied to cell in
vitro or tissues in vivo, it leads to an increase in membrane permeability for molecules which …

Electroporation is being successfully used in biology, medicine, food processing, and
biotechnology, and in some environmental applications. Recent applications also include in …

Gene therapies are revolutionizing medicine by providing a way to cure hitherto incurable
diseases. The scientific and technological advances have enabled the first gene therapies to …

High-frequency bipolar electric pulses have been shown to mitigate undesirable muscle
contraction during irreversible electroporation (IRE) therapy. Here, we evaluate the potential …

DNA electrotransfer is a successful technique for gene delivery into cells and represents an
attractive alternative to virus-based methods for clinical applications including gene therapy …

Electrotransfection (ET) is a nonviral method for delivery of various types of molecules into
cells both in vitro and in vivo. Close to 90 clinical trials that involve the use of ET have been …

Thanks to direct observation and manipulation of DNA in micro/nanofluidic devices, we are
now able to elucidate the relationship between the polymer microstructure and its …

The observation that an application of a pulsed electric field (PEF) resulted in an increased
permeability of the cell membrane has led to the discovery of the phenomenon called …

Electrotransfection is a widely used method for delivering genes into cells with electric
pulses. Although different hypotheses have been proposed, the mechanism of …