[HTML][HTML] MERS coronavirus: diagnostics, epidemiology and transmission

IM Mackay, KE Arden - Virology journal, 2015 - Springer
The first known cases of Middle East respiratory syndrome (MERS), associated with infection
by a novel coronavirus (CoV), occurred in 2012 in Jordan but were reported retrospectively …

[HTML][HTML] MERS-CoV: understanding the latest human coronavirus threat

A Chafekar, BC Fielding - Viruses, 2018 - mdpi.com
Human coronaviruses cause both upper and lower respiratory tract infections in humans. In
2012, a sixth human coronavirus (hCoV) was isolated from a patient presenting with severe …

Rationally engineered Cas9 nucleases with improved specificity

IM Slaymaker, L Gao, B Zetsche, DA Scott, WX Yan… - Science, 2016 - science.org
The RNA-guided endonuclease Cas9 is a versatile genome-editing tool with a broad range
of applications from therapeutics to functional annotation of genes. Cas9 creates double …

Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia

JSM Sabir, TTY Lam, MMM Ahmed, L Li, Y Shen… - Science, 2016 - science.org
Outbreaks of Middle East respiratory syndrome (MERS) raise questions about the
prevalence and evolution of the MERS coronavirus (CoV) in its animal reservoir. Our …

[HTML][HTML] MERS-CoV spillover at the camel-human interface

G Dudas, LM Carvalho, A Rambaut, T Bedford - elife, 2018 - elifesciences.org
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus from camels
causing significant mortality and morbidity in humans in the Arabian Peninsula. The …

[HTML][HTML] Lycorine, a non-nucleoside RNA dependent RNA polymerase inhibitor, as potential treatment for emerging coronavirus infections

YH Jin, JS Min, S Jeon, J Lee, S Kim, T Park, D Park… - Phytomedicine, 2021 - Elsevier
Background: Highly effective novel treatments need to be developed to suppress emerging
coronavirus (CoV) infections such as COVID-19. The RNA dependent RNA polymerase …

[HTML][HTML] Middle East respiratory syndrome: what we learned from the 2015 outbreak in the Republic of Korea

M Oh, WB Park, SW Park, PG Choe… - The Korean journal of …, 2018 - ncbi.nlm.nih.gov
Abstract Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from
a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERSCoV involved …

MERS-CoV as an emerging respiratory illness: a review of prevention methods

S Baharoon, ZA Memish - Travel medicine and infectious disease, 2019 - Elsevier
Abstract Introduction Middle East Respiratory Coronavirus Virus (MERS-CoV) first emerged
from Saudi Arabia in 2012 and has since been recognized as a significant human …

[HTML][HTML] Screening of FDA-approved drugs using a MERS-CoV clinical isolate from South Korea identifies potential therapeutic options for COVID-19

M Ko, SY Chang, SY Byun, A Ianevski, I Choi… - Viruses, 2021 - mdpi.com
Therapeutic options for coronaviruses remain limited. To address this unmet medical need,
we screened 5406 compounds, including United States Food and Drug Administration …

[HTML][HTML] Superior immune responses induced by intranasal immunization with recombinant adenovirus-based vaccine expressing full-length Spike protein of Middle …

MH Kim, HJ Kim, J Chang - PLoS One, 2019 - journals.plos.org
Middle East respiratory syndrome coronavirus (MERS-CoV) causes an acute and severe
lower respiratory illness as well as vomiting, diarrhea, and renal failure. Because no …