PIWI-interacting RNAs (piRNAs) are germline-enriched small RNAs that control transposons
to maintain genome integrity. To achieve this, upon being processed from piRNA precursors …

Mosquito-borne pathogens place an enormous burden on human health. The existing toolkit
is insufficient to support ongoing vector-control efforts towards meeting disease elimination …

Eukaryotic genomes contain virus-derived sequences called endogenous virus elements
(EVEs). The majority of EVEs are related to retroviruses, which integrate into the host …

Piwi‐interacting RNAs (piRNAs) are an animal‐specific class of small non‐coding RNAs that
are generated via a biogenesis pathway distinct from small interfering RNAs (siRNAs) and …

The Asian tiger mosquito, Aedes albopictus, is a competent vector for the majority of
arboviruses. The mosquito innate immune response is a primary determinant for arthropod …

There are several RNA interference (RNAi) pathways in insects. The small interfering RNA
pathway is considered to be the main antiviral mechanism of the innate immune system; …

Transposable elements (TEs) are mobile genetic sequences, which can cause the
accumulation of genomic damage in the lifetime of an organism. The regulation of TEs, for …

Arboviruses are capable to establish long-term persistent infections in mosquitoes that do
not affect significantly the physiology of the insect vectors. Arbovirus infections are controlled …

Abstract Background Small RNAs include different classes essential for endogenous gene
regulation and cellular defence against genomic parasites. However, a comprehensive …

The piRNA pathway is a surveillance system that guarantees oogenesis and adult fertility in
a range of animal species. The pathway is centered on PIWI clade Argonaute proteins and …