[HTML][HTML] Synopsis of guidelines for the clinical management of cerebral cavernous malformations: consensus recommendations based on systematic literature review …

A Akers, RAS Salman, IA Awad, K Dahlem… - …, 2017 - journals.lww.com
BACKGROUND: Despite many publications about cerebral cavernous malformations
(CCMs), controversy remains regarding diagnostic and management strategies …

Cavernous malformations: natural history, diagnosis and treatment

S Batra, D Lin, PF Recinos, J Zhang… - Nature Reviews …, 2009 - nature.com
Cavernous malformations (CMs) consist of dilated vascular channels that have a
characteristic appearance on MRI. CMs are usually found intracranially, although such …

[HTML][HTML] Untreated clinical course of cerebral cavernous malformations: a prospective, population-based cohort study

RAS Salman, JM Hall, MA Horne, F Moultrie… - The Lancet …, 2012 - thelancet.com
Summary Background Cerebral cavernous malformations (CCMs) are prone to bleeding but
the risk of intracranial haemorrhage and focal neurological deficits, and the factors that might …

The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases

KJ Whitehead, AC Chan, S Navankasattusas, W Koh… - Nature medicine, 2009 - nature.com
Cerebral cavernous malformation (CCM) is a common vascular dysplasia that affects both
systemic and central nervous system blood vessels. Loss of function mutations in the CCM2 …

Advances in the treatment and outcome of brainstem cavernous malformation surgery: a single-center case series of 300 surgically treated patients

AA Abla, GP Lekovic, JD Turner, JG De Oliveira… - …, 2011 - journals.lww.com
BACKGROUND: Brainstem cavernous malformations (BSCMs) are relatively uncommon,
low-flow vascular lesions. Because of their relative rarity, relatively little data on their natural …

Natural history of cavernous malformation: systematic review and meta-analysis of 25 studies

S Taslimi, A Modabbernia, S Amin-Hanjani, FG Barker… - Neurology, 2016 - AAN Enterprises
Objective: We pooled the results of studies on natural history of cavernous malformations
(CM) to calculate point estimates and investigate main sources of heterogeneity. Methods …

Management of cerebral cavernous malformations: from diagnosis to treatment

N Mouchtouris, N Chalouhi, A Chitale… - The Scientific World …, 2015 - Wiley Online Library
Cerebral cavernous malformations are the most common vascular malformations and can
be found in many locations in the brain. If left untreated, cavernomas may lead to …

Brainstem cavernous malformations

BA Gross, HH Batjer, IA Awad, BR Bendok - Neurosurgery, 2009 - journals.lww.com
Abstract BRAINSTEM CAVERNOUS MALFORMATIONS (CMs) continue to present a
considerable source of controversy in the neurosurgical community, with an accumulating …

Natural history, evaluation, and management of intracranial vascular malformations

RD Brown Jr, KD Flemming, FB Meyer, HJ Cloft… - Mayo Clinic …, 2005 - Elsevier
Intracranial vascular malformations are seen increasingly in clinical practice, primarily
because of advances in cross-sectional brain and spinal cord imaging. Commonly …

[HTML][HTML] Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice

AC Chan, SG Drakos, OE Ruiz… - The Journal of …, 2011 - Am Soc Clin Investig
Cerebral cavernous malformations (CCMs) are a common type of vascular malformation in
the brain that are a major cause of hemorrhagic stroke. This condition has been …