Introduction Autoimmune hemolytic anemia (AIHA) is classified according to the direct
antiglobulin test (DAT) and thermal characteristics of the autoantibody into warm and cold …

Selective immunoglobulin A deficiency (SIgAD) is the most common primary
immunodeficiency, defined as an isolated deficiency of IgA (less than 0.07 g/L). Although the …

During the last years, studies investigating the intriguing association between
immunodeficiency and autoimmunity led to the discovery of new monogenic disorders, the …

Background Most severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected
individuals are asymptomatic or only exhibit mild disease. In about 10% of cases, the …

Autoimmune Hemolytic Anemia Hemolytic anemias, which are rare, are often caused by
autoimmune destruction of red cells. The hemolysis can be intravascular or extravascular. In …

Background Primary immunodeficiency disease (PID) is a disorder caused by an inherited
flaw in the immune system that increases the susceptibility to infections. Methods In this …

Selective IgA deficiency (sIgAD) is the most common primary immunodeficiency disease
(PID), with an estimated occurrence from about 1: 3000 to even 1: 150, depending on …

Selective IgA deficiency (SIgAD) is the most frequent primary immune defect. Since SIgAD is
not characterized by relevant infectious issues in most cases, it is often diagnosed during the …

Introduction The direct antiglobulin test (DAT) or Coombs test is the cornerstone of the
diagnosis of autoimmune hemolytic anemia (AIHA). It can be performed by several methods …

Immune checkpoint blockade therapy (ICBT) has become a successful cancer treatment
approach in the field of cancer immunotherapy. Blockade of programmed death 1 (PD‐1) …