Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents
Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …
research. Several drugs currently used as therapeutic agents have been developed from …
Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy
CA Dehelean, I Marcovici, C Soica, M Mioc… - Molecules, 2021 - mdpi.com
Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …
nature remains the main supplier of bioactive molecules. The research of natural products is …
Single-cell multi-omics in the medicinal plant Catharanthus roseus
Advances in omics technologies now permit the generation of highly contiguous genome
assemblies, detection of transcripts and metabolites at the level of single cells and high …
assemblies, detection of transcripts and metabolites at the level of single cells and high …
Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …
Exploration of natural compounds with anti-SARS-CoV-2 activity via inhibition of SARS-CoV-2 Mpro
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is a dreaded pandemic in lack of specific …
syndrome coronavirus 2 (SARS-CoV-2), is a dreaded pandemic in lack of specific …
High-throughput transcriptome profiling in drug and biomarker discovery
The development of new drugs is multidisciplinary and systematic work. High-throughput
techniques based on “-omics” have driven the discovery of biomarkers in diseases and …
techniques based on “-omics” have driven the discovery of biomarkers in diseases and …
Fungal endophytes as efficient sources of plant-derived bioactive compounds and their prospective applications in natural product drug discovery: Insights, avenues …
Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …
with many producing pharmacologically valuable specific plant-derived products. This …
Camptothecin's journey from discovery to WHO Essential Medicine: Fifty years of promise
N Khaiwa, NR Maarouf, MH Darwish… - European Journal of …, 2021 - Elsevier
Nature represents a rich source of compounds used for the treatment of many diseases.
Camptothecin (CPT), isolated from the bark of Camptotheca acuminata, is a cytotoxic …
Camptothecin (CPT), isolated from the bark of Camptotheca acuminata, is a cytotoxic …
A review on antifungal and antibacterial activities of some medicinal plants
S Ahmadi, G Ahmadi, H Ahmadi - Micro Nano Bio Aspects, 2022 - mnba-journal.com
The recurrence of fungal infections that occur during allogeneic bone marrow
transplantation, cancer treatment, organ transplantation, and infected wounds has …
transplantation, cancer treatment, organ transplantation, and infected wounds has …
Advances in fingerprint analysis for standardization and quality control of herbal medicines
Herbal drugs or herbal medicines (HMs) have a long-standing history as natural remedies
for preventing and curing diseases. HMs have garnered greater interest during the past …
for preventing and curing diseases. HMs have garnered greater interest during the past …