Microplastics derived from food packaging waste—Their origin and health risks

K Kadac-Czapska, E Knez, M Gierszewska… - Materials, 2023 - mdpi.com
Plastics are commonly used for packaging in the food industry. The most popular
thermoplastic materials that have found such applications are polyethylene (PE) …

Interaction of mancozeb with human hemoglobin: Spectroscopic, molecular docking and molecular dynamic simulation studies

R Quds, MA Hashmi, Z Iqbal, R Mahmood - Spectrochimica Acta Part A …, 2022 - Elsevier
Mancozeb is a broad-spectrum fungicide used extensively in agriculture to protect plants
from numerous diseases. Hemolysis of human erythrocytes on exposure to mancozeb has …

2D‐QSAR and molecular docking studies of carbamate derivatives to discover novel potent anti‐butyrylcholinesterase agents for Alzheimer's disease treatment

H Nour, O Abchir, S Belaidi, FA Qais… - Bulletin of the …, 2022 - Wiley Online Library
Abstract Currently, anti‐butyrylcholinesterase (anti‐BuChE) is among the greatest
therapeutic agents for the treatment of Alzheimer's disease. In this research, a series of 36 …

QSAR modeling, molecular docking, ADMET prediction and molecular dynamics simulations of some 6-arylquinazolin-4-amine derivatives as DYRK1A inhibitors

S Khamouli, S Belaidi, M Bakhouch, S Chtita… - Journal of Molecular …, 2022 - Elsevier
Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a protein kinase
with diverse functions in neuronal development and adult brain physiology. QSAR study was …

Design of Acetylcholinesterase Inhibitors as Promising Anti‐Alzheimer's Agents Based on QSAR, Molecular Docking, and Molecular Dynamics Studies of …

H Nour, MA Hashmi, S Belaidi, A Errougui… - …, 2023 - Wiley Online Library
Cholinesterase inhibitors are promising drugs for the symptomatic treatment of Alzheimer's
disease. In the current study, we explored the quantitative structure activity relationship …

Effect of Date Palm (Phoenix dactylifera) Phytochemicals on Aβ1−40 Amyloid Formation: An in-silico Analysis

Q Zia, MT Rehman, MA Hashmi, S Siddiqui… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease and the most prevalent form of
dementia. The generation of oxygen free radicals and oxidative damage is believed to be …

Physicochemical evaluation of interaction behavior of a series of biocompatible gemini surfactants with hemoglobin: Insights from spectroscopic and computational …

M Akram, M Osama, H Lal, MA Hashmi… - Colloids and Surfaces A …, 2023 - Elsevier
In this study, we investigated the interaction behavior of biodegradable, cationic, oxy-diester
functionalized gemini surfactants N 1, N 1, N 14, N 14-tetramethyl-2, 13-dioxo-N 1, N 14 …

Interaction of the insecticide bioallethrin with human hemoglobin: biophysical, in silico and enzymatic studies

A Arif, MA Hashmi, S Salam, H Younus… - Journal of …, 2023 - Taylor & Francis
Bioallethrin is an insecticide that is widely used in households resulting in human exposure.
Bioallethrin is cytotoxic to human erythrocytes. Here we have studied the interaction of …

In-silico design novel phenylsulfonyl furoxan and phenstatin derivatives as multi-target anti-cancer inhibitors based on 2D-QSAR, molecular docking, dynamics and …

A Guendouzi, L Belkhiri, F Djelti, ZM Zendaoui… - Molecular …, 2024 - Taylor & Francis
ABSTRACT A series of 31 hybrid of phenylsulfonyl furoxan and phenstatin (1a-j, 2a-j, 3a-j, 4
and 5) derivatives, were computationally studied as potential anti-cancer inhibitors against …

Molecular interaction of di-ester bonded cationic Gemini surfactants with pepsin: in vitro and in silico perspectives

M Akram, M Osama, MA Hashmi… - Journal of Biomolecular …, 2023 - Taylor & Francis
The implications of surfactant–enzyme/protein interactions in a variety of fields, including
biotechnology, cosmetics, paints and pharmaceuticals, have attracted a lot of attention in …